Purine Analysis Service
- Qualitative analysis of purine metabolites
- Quantitative analysis of purine content
- Providing foundational research for therapeutic enhancements
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
Purine is a nitrogen-containing heterocyclic compound that serves as the core structural unit of purine bases, which are essential components of DNA and RNA. Its structure comprises a six-membered pyrimidine ring fused to a five-membered imidazole ring. Purine metabolism is critical for cellular proliferation, nucleic acid synthesis, and energy transfer processes. In tumor cells, purine metabolism is typically highly active, as cancer cells require a large supply of nucleotides to support rapid DNA replication and cell division. Changes in purine metabolism and fluctuations in the levels of its metabolites may be associated with the onset, progression, and malignant transformation of cancer. Therefore, monitoring the levels of purine and its metabolites can serve as biomarkers for tumor activity and therapeutic response.
Additionally, purine metabolites, such as uric acid, may accumulate under certain pathological conditions (e.g., gout or renal dysfunction). Monitoring these metabolites provides valuable insights into disease severity and a patient's metabolic health. Given that purines are central to numerous biological processes, their metabolic study is crucial for understanding cellular functions, nucleic acid metabolism, and the mechanisms underlying related diseases.
Figure 1. The Structure of Purine
By leveraging advanced analytical techniques, MtoZ Biolabs offers comprehensive purine analysis services. Supported by our state-of-the-art technology platform and a team of experts in metabolomics, we provide precise and reliable data to ensure the success of your research and clinical studies.
Analysis Workflow
Service Advantages
1. High quality data: We deliver reliable and reproducible results with our advanced LC-MS system.
2. Expertise: Our experienced team of scientists ensures the quality and accuracy of our analysis.
3. Comprehensive report: We provide a detailed report including the experimental procedure, instrument parameters, and results interpretation.
4. Fast turnaround: The process from sample handling to report generation is efficient, shortening the analysis cycle.
Applications
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues and other biological samples. It is essential to select more than 3 materials with the same condition for each sample.
2. Sample Volume
3. Sample Preservation
Store at -80°C to maintain stability.
Note: Provide details on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Purine
4. Raw Data
5. Custom Analysis Report
Our purine analysis service is designed to contribute valuable insights to your research and product development initiatives by delivering precise and dependable results.
How to order?
