Resources

Proteomics Databases



Metabolomics Databases

• • Sugar Alcohol LC-MS Detection

  Sugar alcohols, also known as polyols, are a class of biologically significant natural products with diverse functions. They participate in numerous biochemical reactions within organisms and contribute to various physiological processes, including signal transduction, stabilization of cell membranes, antioxidative mechanisms, and stress responses. Consequently, sugar alcohols and their metabolites hold considerable importance in biochemical research, cell biology, and medical studies. Liquid chromatography

• • Total Redox-Modified Proteome

  Redox modification is an important form of protein modification within organisms, regulating the redox state of proteins and thereby controlling their structure, function, and activity. In general, redox modifications can be divided into oxidation modifications and reduction modifications.

• • Analysing Disulfide Bonds Within Proteins

  Disulfide bonds are a key contributor to protein stability, essential for maintaining the three-dimensional structure and biological functionality of proteins. Therefore, investigating the disulfide bonds within proteins can enhance our understanding of protein structure and function. In biological contexts, disulfide bonds are covalent linkages formed between sulfur atoms within proteins, specifically between cysteine residues. These bonds are crucial for various biological processes, including protein....

• • Protein Interaction Validation

  Protein interaction verification is an essential aspect of biological research, designed to determine whether proteins engage in direct or indirect interactions with one another. This process is instrumental in elucidating intracellular signaling pathways, protein functions, and the pathogenesis of diseases.

• • Mutual Protein Identification

  Identification of interacting proteins refers to the process of recognizing and analyzing interactions between proteins, which is crucial for understanding cellular functions and disease mechanisms. There are various methods for identifying interacting proteins, each with its own advantages and limitations. Here we present a detailed overview of several commonly used methods:

• • Plant Mass Spectrometry Detects Protein Interactions

  Using mass spectrometry to study protein-protein interactions in plants represents a significant direction in contemporary plant proteomics research. By analyzing protein interaction networks, scientists gain deeper insights into physiological processes such as plant growth and development, environmental adaptation, and disease defense. This approach not only identifies direct interactions between specific proteins but also elucidates the composition of protein complexes and their physiological roles in....

• • Mass Spectrometry Combined with Protein

  Mass spectrometry combined with proteomics represents a powerful analytical tool for the identification and quantification of proteins within cells. This process can generally be divided into the following steps:

• • Analysis of Sample Volume Required for Exosome Protein Identification

  Exosomes are vesicles released by cells into the external environment that contain proteins, RNA, and other molecules, which reflect the biological state of their source cells. Identifying exosomal proteins through mass spectrometry typically requires only small sample amounts, though the precise quantity depends on several factors, such as the sensitivity of the mass spectrometer, the purity of the sample, and the desired data depth and coverage.

• • Peptide Detection in Serum

  The detection of peptides in serum is widely used in disease diagnosis, therapeutic monitoring, and biomedical research. Peptides, as a class of small protein fragments with specific biological activities, play crucial roles in many physiological and pathological processes.

• • Target Protein Mass Spectrometry

  Mass spectrometry (MS) is a powerful analytical technique widely used for the identification and quantification of proteins in various samples. This technology plays a critical role in biological research, biomedical studies, and drug development, particularly within the field of proteomics. MS can provide precise molecular weights, structural details, and information on post-translational modifications, such as phosphorylation, glycosylation, or ubiquitination, of proteins. The typical workflow for mass...