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    Spirulina 4D-DIA Quantitative Proteomics

      Spirulina, a microalgae rich in protein, vitamins, and minerals, is not only an efficient nutritional supplement, but also shows great potential in the field of environmental protection and bioenergy research. With the advancement of biotechnology, scientists are increasingly focusing on a deeper understanding of the protein composition and its function in Spirulina, hoping to explore its applications in food science, medicine, and environmental technology. 4D-DIA (four-dimensional data-independent acquisition) quantitative proteomics technology, as an advanced proteomics analysis method, provides us with a powerful tool to achieve this goal.

       

      4D-DIA Quantitative Proteomics Technology

      4D-DIA proteomics is a new generation of DIA technology based on the timsTOFPro mass spectrometer, used for differential quantitative proteomics analysis. Compared with 3D-DIA technology, 4D-DIA proteomics scans faster and more sensitively. At the same time, the addition of the fourth dimension ion mobility separation can obtain DIA data without sacrificing the window cycle speed, while reducing spectrum complexity and improving ion utilization rate, achieving a comprehensive improvement in proteomics in terms of coverage depth, sensitivity, and throughput.

       

      MtoZ Biolabs uses timsTOF Pro to conduct 4D-DIA quantitative proteomics analysis on the proteome of Spirulina, aiding research on the protein expression patterns of Spirulina at different growth stages and environmental conditions, providing valuable information for studying its biological function and potential applications.

       

      Technical Advantages

      1. High Resolution and Accuracy

      4D-DIA technology combines high-performance liquid chromatography (HPLC) separation, high-resolution mass spectrometry (MS) analysis and complex data processing technology, capable of identifying and quantifying thousands to tens of thousands of proteins in a single experiment. The high resolution and accuracy of this technology make it the gold standard in proteomics research.

       

      2. Comprehensive Coverage of the Proteome

      Through 4D-DIA technology, we can achieve comprehensive coverage of the Spirulina proteome, including those low-abundance proteins, which is crucial for understanding the biological functions of Spirulina in depth.

       

      3. High-Throughput Analysis Capability

      Compared to traditional proteomics analysis methods, 4D-DIA technology greatly improves the throughput and efficiency of sample processing, allowing us to quickly process a large number of samples, accelerating the progress of Spirulina research.

       

      4. Wide Dynamic Range

      The technology can cover an extremely wide dynamic range, ensuring the effective detection and quantification of proteins from high abundance to low abundance, which is particularly critical for revealing subtle differences in proteomics.

       

      MtoZ Biolabs' 4D-DIA quantitative proteomics technology platform, combined with our rich proteomics research experience and professional data analysis capabilities, provides strong support for the research and application of Spirulina. We are committed to collaborating with scientists and research institutions worldwide to jointly promote the in-depth development of Spirulina research, and welcome researchers to contact us to learn more about our one-stop solution!

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