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    Thiamine Monophosphate Analysis Service

      Thiamine monophosphate is a phosphorylated derivative of vitamin B1, composed of thiamine (vitamin B1) and a phosphate group, with the chemical formula C12H18N4O4PS+. It plays an important role in energy metabolism and neural function, serving as a crucial bioactive molecule within cells. Thiamine monophosphate acts as an essential coenzyme in energy metabolism, participating in reactions such as pyruvate decarboxylation and α-ketoglutarate decarboxylation, which are vital for the metabolism of carbohydrates and fatty acids. As the active form of vitamin B1, it plays a key role in the normal functioning of the nervous system, aiding in nerve conduction and muscle function. Analyzing the levels of thiamine monophosphate and its metabolites can serve as biomarkers for vitamin B1 deficiency, helping to identify potential nutritional deficiencies early, particularly in high-risk populations such as chronic alcohol dependents and those with metabolic disorders. Thiamine monophosphate's critical role in neural function makes its analysis valuable for studying the effects of neurodegenerative diseases (such as beriberi caused by vitamin B1 deficiency) on nerve function, providing insights for the prevention and treatment of neurological disorders.

       

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      Figure 1. The Structure of Thiamine Monophosphate

       

      MtoZ Biolabs provides a top-notch Thiamine Monophosphate Analysis Service, utilizing our state-of-the-art liquid chromatography-mass spectrometry (LC-MS) platform and experienced metabolomics team. Our analysis service promises comprehensive insights into thiamine monophosphate, ensuring high sensitivity and precision.

       

      Analysis Workflow 

       

      1838446180234285056-WorkflowofThiamineMonophosphateAnalysisService.PNG

       

      Service Advantages

      • Extensive experience in various biological sample preparation techniques
      • Professional standard operating procedure
      • State-of-the-art facilities and equipment for precise analysis
      • Expert team with extensive experience in metabolomics
      • Comprehensive data analysis
      • Excellent customer service and after-service support

       

      Applications

      • Identifying novel disease biomarkers
      • Improving disease diagnostic methods
      • Accelerating the discovery of groundbreaking therapeutics
      • Providing new perspectives on disease mechanisms

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissue, and other biological samples. A minimum of 3 samples under the same condition are required for each type. 

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

      Store at -80°C to maintain stability.

       

      Note: Please provide details on sample collection and handling. 

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Comprehensive Information on Thiamine Monophosphate

      4. Raw Data

      5. Custom Analysis Report

       

      Through our Thiamine Monophosphate Analysis Service, MtoZ Biolabs aims to simplify your research and product development procedures by delivering precise and trustworthy data. Trust MtoZ Biolabs for your thiamine monophosphate analysis needs.

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