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    Thymidine Analysis Service

      Thymidine is a naturally occurring nucleoside composed of the pyrimidine base thymine attached to a deoxyribose sugar molecule. Thymidine is an essential building block of DNA, and it plays a critical role in DNA replication and repair processes. As a key component of the DNA structure, thymidine is incorporated into the DNA strand during cell division, particularly in rapidly proliferating cells.

       

      In tumor cells, the metabolism of thymidine may change, and alterations in its levels and metabolic pathways can be associated with the occurrence, progression, and malignant transformation of cancer. In certain types of cancers, fluctuations in thymidine levels and its metabolites may serve as biomarkers for tumor activity and therapeutic response. Therefore, measuring the levels of thymidine and its metabolites can be used to assess tumor proliferation rates and monitor treatment effectiveness. Additionally, since thymidine can be released from damaged cells or tissues, elevated levels may indicate cell damage, infection, or inflammation. Monitoring its metabolites can help evaluate the extent of tissue damage, the severity of infection, and the intensity of the inflammatory response.

       

      1831236196438233088-TheStructureofThymidine.png

      Figure 1. The Structure of Thymidine

       

      MtoZ Biolabs provides a robust Thymidine Analysis Service, supported by our state-of-the-art liquid chromatography-mass spectrometry (LC-MS) platform and experienced metabolomics team. Our service offers an all-inclusive thymidine analysis, guaranteeing high sensitivity and precision.

       

      Analysis Workflow

       

      1831236284979990528-WorkflowofThymidineAnalysisService.PNG

       

      Service Advantages

      1. High quality data: We deliver reliable and reproducible results with our advanced LC-MS system.

       

      2. Expertise: Our experienced team of scientists ensures the quality and accuracy of our analysis.

       

      3. Comprehensive report: We provide a detailed report including the experimental procedure, instrument parameters, and results interpretation.

       

      4. Fast turnaround: The process from sample handling to report generation is efficient, shortening the analysis cycle.

       

      Applications

      • Qualitative analysis of the metabolites of thymidine
      • Quantitative analysis of thymidine content
      • Providing key basis for drug discovery and development

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues, and other biological specimens. At least 3 materials under the same condition should be selected for each sample.

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

      Samples should be stored at -80°C to ensure stability.

       

      Note: Please provide details on sample collection and handling.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on Thymidine

      4. Raw Data

      5. Custom Analysis Report

       

      With our thymidine analysis service, we strive to support your research and product development efforts by delivering accurate and dependable results.

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