What Are the Protein Protein Interaction Databases?

Protein-Protein Interaction databases primarily record experimentally validated protein interaction data. Here are some key Protein-Protein Interaction databases:

 

BioGRID(Biological General Repository for Interaction Datasets)

BioGRID is a database focused on biological molecular interactions, including protein-protein, protein-DNA, and other types of interaction data.

 

DIP(Database of Interacting Proteins)

DIP is a database that records known protein interactions, aimed at supporting the study of the structure and function of biological molecular complexes. It contains experimentally validated interactions.

 

IntAct

IntAct is an open-source protein interaction database maintained by the European Bioinformatics Institute (EBI). It provides detailed protein interaction information, including experimental conditions and methods.

 

MINT

Molecular Interactions Database, focusing on experimentally validated protein interactions.

 

STRING(Search Tool for the Retrieval of Interacting Genes/Proteins)

The STRING database provides extensive information about proteins and their predicted interactions. This includes direct (physical) and indirect (functional) associations, spanning a broad range of data sources, including experimental data, computational predictions, co-expression networks, and text mining results from the literature.

 

BIND

Stores interactions of proteins, compounds, and dimers.

 

HPRD

Human Protein Reference Database, focusing on information including cell location, expression, protein interactions, phosphorylation sites, and disease associations.

 

HPIDb (Host-Pathogen Interaction Database)

HPIDb focuses on protein-protein interactions between hosts and pathogens.