11-Dehydrocorticosterone Analysis Service
- Discovering new biomarkers for disease
- Enhancing disease diagnosis and prognosis
- Accelerating the discovery of novel therapeutics
- Gaining new insights into disease mechanisms
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
11-Dehydrocorticosterone (11-DHC) is an important metabolite of adrenal corticosteroids and belongs to the class of glucocorticoids. Structurally similar to corticosterone, 11-DHC is primarily produced through the catalytic reaction of 11β-hydroxysteroid dehydrogenase. In vivo, 11-DHC plays a crucial role in regulating glucose metabolism, stress response, and immune function. Particularly in the kidneys, 11-DHC acts as a ligand for glucocorticoid receptors, influencing mineral balance and blood pressure regulation. In recent years, research on 11-DHC has been expanding, particularly in the fields of metabolic diseases, neuroendocrine disorders, and renal pathology. The exploration of its metabolic pathways and mechanisms has revealed potential links between 11-DHC and various disease states, especially in pathological conditions such as metabolic disorders, obesity, and hypertension. Fluctuations in 11-DHC levels are closely related to the progression of these diseases. Therefore, studying the metabolic dynamics and biological effects of 11-DHC is essential for understanding the regulatory mechanisms of glucocorticoid metabolism. Moreover, 11-DHC has emerged as a potential target and biomarker in drug development, further enhancing its application in biomedical research.
Figure 1. The Structure of 11-Dehydrocorticosterone
MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider, providing advanced metabolomics, proteomics and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. MtoZ Biolabs utilizes an LC-MS-based metabolomics research platform for the analysis of 11-dehydrocorticosterone. We ensure the accuracy of the quantification of 11-dehydrocorticosterone and its metabolites, as well as the comprehensiveness and precision of metabolite identification. If you are interested in our 11-dehydrocorticosterone analysis service, please feel free to contact us at any time, and we will be fully committed to providing you with high-quality analytical services and technical support.
Analysis Workflow
Service Advantages
1. Advance Analysis Platform: MtoZ Biolabs established an advanced 11-dehydrocorticosterone analysis platform, guaranteeing reliable, fast, and highly accurate analysis service.
2. One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.
3. High-Data-Quality: Extensive data coverage with rigorous quality control. Our advanced analysis platform consolidates all 11-dehydrocorticosterone analysis data, delivering clients a detailed and comprehensive data report.
4. Quick Turnaround: We offer a fast analysis process to ensure that clients receive high-quality data within a short time.
Applications
Sample Submission Requirements
1. Sample Types
Acceptable sample types include serum, plasma, urine, tissues, and other biological samples. Each sample must contain at least 3 materials under the same conditions.
2. Sample Volume
3. Sample Preservation
All samples must be stored at -80°C to maintain stability. Please provide all relevant details on sample collection and handling.
Deliverables
1. Comprehensive Experimental Details （Materials, Instruments and Methods,etc.）
2. Relevant LC-MS parameters
3. Detailed information on 11-dehydrocorticosterone Analysis
4. Raw data
5. Custom analysis report
Through our 11-Dehydrocorticosterone Analysis Service, we strive to support your research and development work by providing accurate, reliable, and insightful results.
How to order?
