17α-Estradiol Analysis Service
- Continuously refined protocols and cutting-edge analytical tools
- Expert experimental planning
- Rapid processing times
- Exceptional precision, selectivity, and sensitivity
- Qualitative analysis of 17α-estradiol and its metabolites
- Quantitative analysis of 17α-estradiol concentration
- Providing the basis for improvement in therapeutic and research applications
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
17α-Estradiol is a naturally occurring stereoisomer of estradiol, a potent estrogen steroid hormone that plays a role in regulating the reproductive system and the development of secondary sexual characteristics. Unlike 17β-estradiol, which is the most active form of estrogen in humans, 17α-estradiol has weaker estrogenic activity and is characterized by a hydroxyl group in the α-configuration at the C17 position.
Although 17α-estradiol has weaker estrogenic activity, studies suggest that it may have neuroprotective effects, potentially helping to slow the progression of neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease. Quantitative analysis of 17α-estradiol and its metabolites can provide deeper insights into its distribution, metabolic pathways, and pharmacokinetic properties in the body, serving as foundational data for the development of new therapeutic drugs. The quantitative analysis of 17α-estradiol and its metabolites is of great importance in the diagnosis and monitoring of endocrine-related diseases. For example, changes in 17α-estradiol levels can serve as an auxiliary diagnostic marker in conditions such as hypogonadism or other endocrine disorders. Additionally, tracking the concentration changes of its metabolites can be used to assess disease progression or the effectiveness of treatment.
Figure 1. The Structure of 17α-Estradiol
MtoZ Biolabs offers an advanced 17a-Estradiol Analysis Service, based on our cutting-edge liquid chromatography-mass spectrometry (LC-MS) platform and supported by our experienced metabolomics team. We offer a comprehensive 17α-estradiol analysis, ensuring high sensitivity and precision.
Analysis Workflow
Service Advantages
Applications
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues and other biological samples. At least 3 samples of the same condition are required for each analysis.
2. Sample Volume
3. Sample Preservation
Samples should be stored at -80°C to ensure stability.
Note: Please provide detailed information on sample collection and processing.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 17a-Estradiol
4. Raw Data
5. Custom Analysis Report
With our 17α-estradiol analysis service, we aim to enhance your research and product development by delivering accurate and reliable results.
How to order?
