17α-Ethinylestradiol Analysis Service

17α-Ethinylestradiol (EE2) is a synthetic estrogen whose structure resembles that of the natural estrogen estradiol. The chemical structure of EE2 includes an ethynyl group substituted at the 17α position, a modification that imparts significant biological activity and stability, thereby markedly reducing its metabolic rate in the body and prolonging its duration of action. Metabolomics analysis, utilizing high-throughput techniques such as mass spectrometry and nuclear magnetic resonance, can comprehensively elucidate the metabolic pathways and mechanisms of EE2 within the body. 

 

Compared to traditional metabolic analysis methods, metabolomics can detect a wider variety of metabolites and concentration changes, providing more comprehensive information on the metabolic network. Through this approach, both primary and secondary metabolic pathways of EE2 can be identified, including biochemical reactions involving specific enzymes, which helps in understanding the metabolic differences of EE2 in different tissues and organs. Metabolomics analysis can identify various metabolites of EE2 and their structural characteristics, including active metabolites and potentially toxic ones. This is crucial for elucidating the pharmacological effects and toxicological properties of EE2. For instance, some metabolites may have greater biological activity or toxicity than the parent drug; metabolomics analysis can help discover these key metabolites and investigate their potential impacts.

 



Figure1. The Structure of 17α-Ethinylestradiol

 

MtoZ Biolabs is proud to offer a high-end 17α-Ethinylestradiol Analysis Service. Utilizing our state-of-the-art liquid chromatography-mass spectrometry (LC-MS) platform and a team of metabolomics experts, we can provide a thorough metabolomics analysis of 17α-ethinylestradiol, ensuring unparalleled sensitivity and accuracy.

 

Analysis Workflow 

 



 

Service Advantages

1. High quality data: We deliver reliable and reproducible results with our advanced LC-MS system.

 

2. Expertise: Our experienced team of scientists ensures the quality and accuracy of our analysis.

 

3. Comprehensive report: We provide a detailed report including the experimental procedure, instrument parameters, and results interpretation.

 

4. Fast turnaround: The process from sample handling to report generation is efficient, shortening the analysis cycle.

 

Applications

• Qualitative analysis of the metabolites of 17α-ethinylestradiol
• Quantitative analysis of 17α-ethinylestradiol content
• Provide a basis for pharmaceutical research and product development

 

Sample Submission Requirements

1. Sample Types

Serum, plasma, urine, tissues, and other biological samples. A minimum of 3 materials with the same condition is required for each sample. 

 

2. Sample Volume

• Animal tissue ≥ 100 mg
• Plant tissue ≥ 200 mg
• Serum/ Plasma ≥ 200 μL
• Urine ≥ 2 mL

 

3. Sample Preservation

Samples should be stored at -80°C to maintain stability.

 

Note: Please provide detailed information about sample collection and handling procedures.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on 17α-Ethinylestradiol

4. Raw Data

5. Custom Analysis Report

 

Through our 17α-ethinylestradiol analysis service, we strive to support your research and product development endeavors by delivering precise and reliable results.