2-Aminobutyric Acid Analysis Service

2-Aminobutyric acid is a non-protein amino acid with important metabolic functions in various organisms. It is a key intermediate in the glutathione metabolism pathway and plays a crucial role in regulating cellular antioxidant capacity, detoxification, and amino acid metabolism. As an antioxidant, 2-Aminobutyric acid helps maintain intracellular levels of reduced glutathione, protecting cells from oxidative stress damage. Additionally, 2-Aminobutyric acid metabolism is closely related to cystathionine synthesis, the methionine cycle, and the balance of S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH).

 

Abnormal metabolism of 2-Aminobutyric acid is linked to various physiological processes and pathological conditions, such as neurodegenerative diseases, liver diseases, and oxidative stress-related disorders. Studies have shown that 2-Aminobutyric acid has protective effects in the nervous system, reducing oxidative stress damage to neurons. In the liver, 2-Aminobutyric acid is involved in glutathione synthesis, aiding in detoxification and maintaining liver health. Furthermore, 2-Aminobutyric acid plays a critical role in regulating the cellular redox balance, making it essential for studying oxidative stress and antioxidant defense mechanisms.

 



Figure 1. Molecular Structure of 2-Aminobutyric Acid

 

MtoZ Biolabs utilizes liquid chromatography-tandem mass spectrometry (LC-MS/MS) to conduct detailed quantitative and qualitative analyses of 2-Aminobutyric Acid and its metabolites. This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of 2-Aminobutyric Acid in complex biological matrices.

 

Analysis Workflow

 



 

Service Advantages

 

 

 

Sample Submission Requirements

Sample Types

Serum, plasma, urine, tissue homogenates, and other biological samples.

 

Sample Volume

At least 200 μL of liquid sample or 200 mg of tissue sample.

 

Sample Preservation

Store and transport samples at -80°C.

 

Applications

• Neuroscience Research: Investigate the protective mechanisms of 2-Aminobutyric acid in neurodegenerative diseases.
• Liver Disease Research: Evaluate the role of 2-Aminobutyric acid in liver detoxification and metabolism.
• Oxidative Stress Research: Study the role of 2-Aminobutyric acid in cellular antioxidant processes.
• Metabolic Research: Explore the functions of 2-Aminobutyric acid in glutathione and amino acid metabolism.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on 2-Aminobutyric Acidand Their Metabolites

4. Raw Data

5. Custom Analysis Report

 

Our 2-Aminobutyric acid analysis service provides high-quality data support, advancing your scientific research and foundational applications. For any inquiries or requirements, please contact us.