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    2-Methylbutyroylcarnitine Analysis Service

      2-Methylbutyroylcarnitine is an acylcarnitine molecule naturally produced in the body through the β-oxidation of isoleucine. It consists of a straight-chain 2-methylbutyroyl group combined with a carnitine molecule. Changes in the levels and metabolic processes of 2-methylbutyroylcarnitine may be associated with the occurrence, development, and outcome of certain metabolic disorders or disease states. Elevated levels of 2-methylbutyroylcarnitine and other acylcarnitines are frequently observed in patients with inherited metabolic diseases, such as isoleucine metabolism disorders. Therefore, measuring the levels of 2-methylbutyroylcarnitine and its metabolites can serve as biomarkers for metabolic disease activity and therapeutic efficacy.

       

      Additionally, since 2-methylbutyroylcarnitine can be produced under conditions of metabolic dysfunction or drug influence, elevated levels may indicate disorders in fatty acid oxidation or other metabolic diseases. Monitoring its metabolites can help assess a patient's metabolic function and the progression of disease, providing valuable insights for clinical diagnosis and optimizing treatment strategies.

       

      1830453046690828288-TheStructureof2-Methylbutyroylcarnitine.png

      Figure 1. The Structure of 2-Methylbutyroylcarnitine

       

      MtoZ Biolabs offers specialized 2-methylbutyroylcarnitine analysis services, utilizing advanced analytical techniques and a high-standard technology platform. Our expert metabolomics team ensures precise and reliable data, providing strong support for your drug development, clinical studies, and metabolic research, helping your research achieve success.

       

      Analysis Workflow

       

      1830893505737248768-Workflowof2-MethylbutyroylcarnitineAnalysisService.PNG

       

      Service Advantages

      High quality data: We deliver reliable and reproducible results with our advanced LC-MS system.

       

      Expertise: Our experienced team of scientists ensures the quality and accuracy of our analysis.

       

      Comprehensive report: We provide a detailed report including the experimental procedure, instrument parameters, and results interpretation.

       

      Fast turnaround: The process from sample handling to report generation is efficient, shortening the analysis cycle.

       

      Applications

      • Qualitative analysis of 2-methylbutyroylcarnitine metabolites
      • Quantitative analysis of 2-methylbutyroylcarnitine content
      • Providing a foundation for advancements in the field

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues and other biological samples. At least 3 samples of the same condition are required for each type.

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

      Preserve at -80°C for stability.

       

      Note: Please provide detailed information on sample collection and handling.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on 2-Methylbutyroylcarnitine

      4. Raw Data

      5. Custom Analysis Report

       

      If you have any requirements for 2-methylbutyroylcarnitine analysis services or would like to learn more, please feel free to contact us. MtoZ Biolabs is committed to providing professional and efficient services to support the success of your research and production. We look forward to assisting you in your research endeavors!

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