2'-O-methylcytidine Analysis Service
- Extensive expertise in handling various biological samples and extracting metabolites.
- State-of-the-art mass spectrometry platforms: UPLC-MS, GC-MS, MRM method.
- Strict quality control to ensure reliable results.
- Comprehensive statistical and bioinformatics analysis.
- Personalized service to meet various research needs.
- Disease biomarker discovery
- Drug discovery and development
- Mechanistic studies of diseases
- Samples should be stored at -80℃ and shipped with dry ice.
- We recommend providing at least 3 samples of similar conditions for each type of sample.
- Please provide details on sample collection and handling.
- Other sample types, please contact us for more details.
2'-O-methylcytidine is a modified nucleoside found in various types of RNA, where the 2'-hydroxyl group of the ribose sugar is methylated. This modification is critical for the stability, function, and regulation of RNA molecules, particularly in tRNA, rRNA, and mRNA. Structurally, 2'-O-methylcytidine retains the basic cytidine nucleobase but incorporates a methyl group at the 2' position of the ribose, which can influence RNA folding and interaction with other biomolecules.
Figure 1. The Structure of 2'-O-methylcytidine
2'-O-methylcytidine has been increasingly studied in the context of RNA biology, where RNA modifications are understood to play vital roles in cellular processes such as protein translation, RNA splicing, and gene expression regulation. Modifications like 2'-O-methylcytidine contribute to the fine-tuning of RNA stability and its resistance to degradation by nucleases, making them important for proper cellular function. Furthermore, alterations in RNA methylation patterns, including 2'-O-methylcytidine, have been linked to a range of human diseases, including cancer and metabolic disorders, as well as responses to viral infections.
Accurate analysis of 2'-O-methylcytidine is essential for understanding its functional role in health and disease. The study of 2'-O-methylcytidine is particularly relevant for the development of RNA-based therapeutics and vaccines, as well as for exploring its potential as a biomarker in disease diagnosis and treatment response monitoring.
MtoZ Biolabs is proud to introduce our latest analysis service: 2'-O-methylcytidine Analysis. We utilize advanced ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) to accurately quantify 2'-O-methylcytidine in different types of samples with high sensitivity and reproducibility.
Analysis Workflow
Service Advantages
Applications
Our 2'-O-methylcytidine analysis service is applicable in various research fields including:
Sample Submission Requirements
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 2'-O-methylcytidine
4. Raw Data
5. Custom Analysis Report
Please feel free to contact us for further information. MtoZ Biolabs is always here to provide comprehensive metabolomics and proteomics services to accelerate your research!
How to order?
