3-Hydroxyphenylacetic Acid Analysis Service

3-Hydroxyphenylacetic acid (3-HPAA) is a significant metabolite widely present in humans and various organisms. It is an intermediate product in tyrosine metabolism, playing a crucial role in various physiological processes and diseases. The levels of 3-HPAA can serve as biomarkers for metabolic disorders such as phenylketonuria and tyrosinemia. Moreover, studies have indicated that 3-HPAA possesses potential antihypertensive effects, possibly by regulating vasodilation and providing antioxidant properties. Therefore, precise quantitative and qualitative analysis of 3-HPAA is essential for clinical diagnostics, metabolic research, and drug development.

 

Figure 1. Molecular Structure of 3-Hydroxyphenylacetic Acid

 

MtoZ Biolabs offers 3-Hydroxyphenylacetic Acid Analysis Service using ultra-performance liquid chromatography-mass spectrometry (UPLC-MS). This advanced method combines the separation capabilities of UPLC with the detection power of MS, ensuring high sensitivity and specificity in 3-HPAA detection.

 

Analysis Workflow

 



 

Service Advantages

1. High Sensitivity and Precision

UPLC-MS/MS provides highly sensitive and accurate measurements, suitable for detecting low concentrations of 3-HPAA.

 

2. Rapid and Efficient

Optimized sample preparation and fast analysis ensure quick and efficient processing.

 

3. Wide Applicability

Suitable for various biological samples, including blood, urine, and tissues.

 

4. Accurate and Reliable Data

Ensures high reproducibility and low error rates, supporting both research and clinical applications, providing reliable and specific results.

 

Sample Submission Requirements

1. Sample Types

Serum, plasma, urine, tissue homogenates, and other biological samples.

 

2. Sample Volume

At least 200 μL of liquid sample or 200 mg of solid sample.

 

3. Sample Preservation

Store at -80°C to maintain stability.

 

Note: Provide details on sample collection and handling.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on 3-Hydroxyphenylacetic Acid

4. Raw Data

5. Custom Analysis Report

 

Our 3-Hydroxyphenylacetic Acid Analysis Service provides high-quality data support, advancing your scientific research and applications. For any inquiries or requirements, please contact us.