3-methylcytidine Analysis Service
- Advanced HPLC-MS/MS system for precise quantification
- Expertise in metabolomics and mass spectrometry
- Comprehensive data analysis
- High-throughput analysis capability
- Competitive pricing
- Studying the role of m3C in biological processes
- Investigating the changes in m3C levels in disease conditions
- Drug discovery and development
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
3-Methylcytidine (m3C), with the chemical formula C₁₀H₁₅N₃O₅, is a rare nucleoside found in transfer RNA (tRNA) and ribosomal RNA (rRNA). It is a derivative of cytidine, formed by the combination of ribose and 3-methylcytosine, where the cytosine base is modified with a methyl group at the 3rd position. This methylation at the 3rd position prevents the formation of standard base pairs, thus influencing RNA structure and function. As a unique modification, m3C plays a crucial role in regulating RNA processes, including the stability and translation of RNA molecules. Its presence in tRNA and rRNA has been linked to cellular stress responses and the fine-tuning of gene expression. Additionally, the disruption or aberrant expression of m3C has been associated with various diseases, including cancer, making it an important target for biomarker research.
Figure 1. The Structure of 3-methylcytidine
At MtoZ Biolabs, we use High-Performance Liquid Chromatography-Tandem Mass Spectrometry (HPLC-MS/MS) for precise quantification of m3C, which offers high sensitivity and accurate quantification. Our team of experts with profound experience in mass spectrometry and metabolomics can help researchers to investigate the role of m3C in various biological processes.
Analysis Workflow
Service Advantages
Applications
Our service can be used for:
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.
2. Sample Volume
3. Storage and Shipping
Samples should be stored at -80℃ and shipped with dry ice.
Note: Please provide details on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 3-methylcytidine
4. Raw Data
5. Custom Analysis Report
For more information on our 3-methylcytidine Analysis Service, please contact us at MtoZ Biolabs. Our team is committed to providing high-quality services to meet your research needs.
How to order?
