3β-Glycocholic Acid Analysis Service
- Measure the levels of bile acid metabolites to study their roles in the bile acid cycle, revealing potential functions in liver and biliary diseases.
- Use metabolites as biomarkers to monitor the progression and treatment of liver and biliary diseases, providing insights for clinical diagnosis.
- Analyze the pathways of metabolites in metabolic diseases, exploring their roles in lipid metabolism and cholesterol regulation.
- Investigate the impact of metabolites to guide the development of bile acid-related therapeutics and optimize treatment strategies.
3β-Glycocholic acid (βGCA) and 3α-glycocholic acid (αGCA) are stereoisomers of glycocholic acid, distinguished by the orientation of the hydroxyl group at the 3-position. This stereochemical variation leads to distinct metabolic pathways and functional differences in the body. Research indicates that βGCA may have a unique role in bile acid metabolism, particularly in liver and biliary diseases. Therefore, precise analysis of βGCA is essential for understanding its physiological and pathological roles.
Figure 1. Molecular Structure of 3β-Glycocholic Acid
MtoZ Biolabs offers 3β-Glycocholic Acid Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in βGCA detection.
Analysis Workflow
Service Advantages
1. High Sensitivity and Precision
HPLC-MS/MS provides highly sensitive and accurate measurements, suitable for detecting low concentrations of βGCA.
2. Rapid and Efficient
Optimized sample preparation and fast analysis ensure quick and efficient processing.
3. Wide Applicability
Suitable for various biological samples, including blood, urine, feces, and tissues.
4. Accurate and Reliable Data
Ensures high reproducibility and low error rates, supporting both research and clinical applications, providing reliable and specific results.
Sample Submission Requirements
Make sure the sample volume is greater than 0.2 g or 0.2 mL. For detailed sample submission information, please contact our customer service.
Applications
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 3β-Glycocholic Acid
4. Raw Data
5. Custom Analysis Report
MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into βGCA's extensive physiological roles through top-tier analytical techniques and expert services.
How to order?
