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    4-Hydroxy-3-methoxymandelic Acid Analysis Service

      4-Hydroxy-3-methoxymandelic acid, also known as vanillylmandelic acid (VMA), is a metabolite of the catecholamines dopamine and epinephrine. It can be derived from the breakdown of catecholamines in the adrenal glands and sympathetic nerves. Structurally, VMA is a member of the class of compounds known as O-methylated hydroxybenzoic acids. These are hydroxybenzoic acids carrying a methoxy group at the benzene ring.

       

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      Figure 1. The Structure of 4-Hydroxy-3-methoxymandelic Acid

       

      Studying 4-Hydroxy-3-methoxymandelic acid is pivotal for biochemical and physiological research. It serves as an excellent biomarker for diagnosing diseases like neuroblastoma, pheochromocytoma, and paraganglioma. In addition, VMA is a crucial factor in stress response, blood pressure regulation, and neurotransmission.

       

      Our team of experts can help you detect and quantify 4-Hydroxy-3-methoxymandelic acid in various types of samples. We offer a comprehensive 4-Hydroxy-3-methoxymandelic Acid Analysis Service, from sample preparation, metabolite extraction, separation, to detection and quantification.

       

      Analysis Workflow

       

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      Service Advantages

      • Extensive expertise in handling various biological samples and extracting metabolites.
      • State-of-the-art mass spectrometry platforms: LC-MS, GC-MS, MRM method.
      • Strict quality control to ensure reliable results.
      • Comprehensive statistical and bioinformatics analysis.
      • Personalized service to meet various research needs.

       

      Applications

      • Disease Diagnosis
      • Drug Metabolism Study
      • Nutritional Research
      • Biomarker Discovery

       

      Sample Submission Requirements

       

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      • Samples should be stored at -80℃ and shipped with dry ice.
      • We recommend providing at least 3 samples of similar conditions for each type of sample.
      • Please provide details on sample collection and handling.
      • Other sample types, please contact us for more details.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on 4-Hydroxy-3-methoxymandelic Acid 

      4. Raw Data

      5. Custom Analysis Report

       

      We are dedicated to providing the best service to our clients, and we look forward to working with you on your 4-Hydroxy-3-methoxymandelic Acid Analysis project.

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