4-Hydroxyhippuric Acid Analysis Service

4-Hydroxyhippuric acid (4-HHA) is a derivative of hippuric acid commonly found in human and animal urine. It is primarily produced through the metabolism of phenolic compounds, making it a key marker for assessing exposure to these substances. Additionally, 4-HHA is important in studying the human microbiome, metabolic disorders, and environmental toxicology. Accurate quantitative and qualitative analysis of 4-HHA is essential in clinical diagnostics, environmental research, and biomedical studies.

 

Figure 1. Molecular Structure of 4-Hydroxyhippuric Acid

 

MtoZ Biolabs offers 4-Hydroxyhippuric Acid Analysis Service using ultra-performance liquid chromatography-mass spectrometry (UPLC-MS). This advanced method combines the separation capabilities of UPLC with the detection power of MS, ensuring high sensitivity and specificity in 4-HHA detection.

 

Analysis Workflow

 



 

Service Advantages

1. High Sensitivity and Precision

UPLC-MS/MS provides highly sensitive and accurate measurements, suitable for detecting low concentrations of 4-HHA.

 

2. Rapid and Efficient

Optimized sample preparation and fast analysis ensure quick and efficient processing.

 

3. Wide Applicability

Suitable for various biological samples, including blood, urine, and tissues.

 

4. Accurate and Reliable Data

Ensures high reproducibility and low error rates, supporting both research and clinical applications, providing reliable and specific results.

 

Sample Submission Requirements

1. Sample Types

Serum, plasma, urine, tissue homogenates, and other biological samples.

 

2. Sample Volume

At least 200 μL of liquid sample or 200 mg of solid sample.

 

3. Sample Preservation

Store at -80°C to maintain stability.

 

Note: Provide details on sample collection and handling.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on 4-Hydroxyhippuric Acid

4. Raw Data

5. Custom Analysis Report

 

MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into 4-HHA's extensive physiological roles through top-tier analytical techniques and expert services.