4-Hydroxyphenylacetic Acid Analysis Service

4-Hydroxyphenylacetic acid (4-HPA) is a naturally occurring organic acid widely found in various plants, microorganisms, and animals. It is an important intermediate in tyrosine metabolism and exhibits multiple biological activities, including antibacterial, antioxidant, and anti-inflammatory effects. In the food industry, 4-HPA is used as a natural preservative to extend product shelf life. In the pharmaceutical field, 4-HPA is studied for its anti-inflammatory and anticancer properties, with potential applications in treating various diseases. Additionally, 4-HPA can serve as a biomarker for metabolic disorders such as phenylketonuria and tyrosinemia. Therefore, accurate quantitative and qualitative analysis of 4-HPA is essential for food science, pharmaceutical research, and clinical diagnostics.

Figure 1. Molecular Structure of 4-Hydroxyphenylacetic Acid

MtoZ Biolabs offers 4-Hydroxyphenylacetic Acid Analysis Service using ultra-performance liquid chromatography-mass spectrometry (UPLC-MS). This advanced method combines the separation capabilities of UPLC with the detection power of MS, ensuring high sensitivity and specificity in 4-HPA detection.

Analysis Workflow

Service Advantages

1. High Sensitivity and Precision

UPLC-MS/MS provides highly sensitive and accurate measurements, suitable for detecting low concentrations of 4-HPA.

2. Rapid and Efficient

Optimized sample preparation and fast analysis ensure quick and efficient processing.

3. Wide Applicability

Suitable for various biological samples, including blood, urine, and tissues.

4. Accurate and Reliable Data

Ensures high reproducibility and low error rates, supporting both research and clinical applications, providing reliable and specific results.

Sample Submission Requirements

For detailed sample submission instructions, please consult our technical team.

Applications

• Investigate the preservative effects of 4-HPA in food to extend shelf life.
• Evaluate the potential therapeutic applications of 4-HPA in anti-inflammatory and anticancer treatments.
• Diagnose and monitor metabolic disorders, such as phenylketonuria and tyrosinemia, by detecting 4-HPA levels.
• Study the metabolic mechanisms of 4-HPA in microorganisms and its role in fermentation.

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on 4-Hydroxyphenylacetic Acid

4. Raw Data

5. Custom Analysis Report

Our 4-Hydroxyphenylacetic Acid Analysis Service provides high-quality data support, advancing your scientific research and applications. For any inquiries or requirements, please contact us.