5-β-Cholanic Acid-3α-Ol-6-One Analysis Service

5-β-Cholanic acid-3α-ol-6-one , also referred to as 6-ketolithocholic acid (6-ketoLCA), is an important intermediate metabolite in bile acid metabolism, recognized for its specific biological activity. 6-ketoLCA is synthesized from lithocholic acid via the action of cytochrome P450 (CYP) isoforms CYP3A1 and CYP3A2. This compound is generated through enzyme-catalyzed reactions within the bile acid metabolism pathway and is widely distributed in the liver, bile, and intestines. Research has shown that 6-ketoLCA plays a vital role in bile acid metabolism, cholesterol regulation, and the maintenance of liver function. Abnormal levels of 6-ketoLCA are closely associated with various metabolic and liver diseases, making precise analysis of this compound crucial for understanding its functions in both physiological and pathological conditions.

 

Figure 1. Molecular Structure of 5-β-Cholanic Acid-3α-Ol-6-One

 

To support research endeavors, MtoZ Biolabs offers specialized 5-β-Cholanic Acid-3α-Ol-6-One Analysis Service. We utilize advanced high performance liquid chromatography (HPLC) and mass spectrometry (MS) technologies to deliver high-sensitivity and high-specificity quantitative analysis, supporting scientific research and application development.

 

Analysis Workflow

 



 

Service Advantages

1. High Sensitivity

Detects very low concentrations of 6-ketoLCA accurately.

 

2. High Specificity

Differentiates 6-ketoLCA from other compounds using mass spectrometry.

 

3. Rapid Analysis

Efficient sample preparation and fast detection processes for high-throughput analysis.

 

4. High Accuracy

Strict quality control ensures accuracy and reproducibility.

 

5. Versatility

Capable of analyzing 6-ketoLCA and its related metabolites.

 

Sample Submission Requirements

 



For detailed sample submission instructions, please consult our technical team.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on 5-β-Cholanic Acid-3α-Ol-6-One

4. Raw Data

5. Custom Analysis Report

 

Our 5-β-Cholanic Acid-3α-Ol-6-One Analysis Service provides high-quality data support, advancing your scientific research and applications. For any inquiries or requirements, please contact us.