7-Ketodeoxycholic Acid Analysis Service

7-Ketodeoxycholic acid (7-KDCA) is a significant intermediate in bile acid metabolism, classified as a secondary bile acid. It is produced through the enzymatic oxidation of primary bile acids, such as deoxycholic acid, by intestinal microorganisms. Bile acids are essential for the digestion and absorption of fats, as well as maintaining the bile acid pool within the body. The synthesis and distribution of 7-KDCA are closely linked to liver function, the balance of the intestinal microbiome, and the overall bile acid metabolism. Investigating 7-KDCA not only facilitates a deeper understanding of the intricate mechanisms underlying bile acid metabolism but also uncovers the effects of liver diseases, metabolic disorders, and drug interactions on bile acid homeostasis. Analyzing 7-KDCA provides crucial insights into various disease states and metabolic pathways, offering valuable support for both clinical and basic research.

 

Figure 1. Molecular Structure of 7-Ketodeoxycholic Acid

 

MtoZ Biolabs offers 7-Ketodeoxycholic Acid Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in 7-KDCA detection.

 

Analysis Workflow

 



 

Service Advantages

1. High Sensitivity and Precision

HPLC-MS/MS provides highly sensitive and accurate measurements, suitable for detecting low concentrations of 7-KDCA.

 

2. Rapid and Efficient

Optimized sample preparation and fast analysis ensure quick and efficient processing.

 

3. Wide Applicability

Suitable for various biological samples, including blood, urine, feces, and tissues.

 

4. Accurate and Reliable Data

Ensures high reproducibility and low error rates, supporting both research and clinical applications, providing reliable and specific results.

 

Sample Submission Requirements

 



For detailed sample submission instructions, please consult our technical team.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on 7-Ketodeoxycholic Acid

4. Raw Data

5. Custom Analysis Report

 

MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into 7-KDCA's extensive physiological roles through top-tier analytical techniques and expert services.