• Home
  • Biopharmaceutical Research Services
  • Multi-Omics Services
  • Support
  • /assets/images/icon/icon-email-2.png

    Email:

    info@MtoZ-Biolabs.com

    8-hydroxyadenosine Analysis Service

      8-Hydroxyadenosine is a crucial biomarker for oxidative stress and cellular damage, derived from the oxidation of adenosine. Structurally, 8-hydroxyadenosine is an adenosine derivative where the 8th position of the purine ring has been hydroxylated, forming a highly reactive compound. This modification results from the interaction between adenosine and reactive oxygen species (ROS), which are often produced during oxidative stress conditions.

       

      8-hydroxyadenosine plays a significant role in assessing oxidative damage in various biological systems. It is not only a marker of oxidative stress but also an indicator of DNA damage, as it can lead to the formation of 8-hydroxydeoxyguanosine (8-OHdG), a well-known DNA lesion. The presence and concentration of 8-hydroxyadenosine can be indicative of the extent of cellular and tissue damage and provide insights into the underlying pathological conditions.

       

      Elevated levels of 8-hydroxyadenosine have been associated with increased risk and progression of the diseases, such as cancer, cardiovascular diseases, and neurodegenerative disorders, making it a valuable biomarker for both diagnostic and prognostic purposes. The analysis of 8-hydroxyadenosine can help in understanding the mechanisms of disease development and the impact of oxidative stress on cellular health.

       

      1833057161036025856-TheStructureof8-hydroxyadenosine.png

       

      Figure 1. The Structure of 8-hydroxyadenosine

       

      MtoZ Biolabs is pleased to offer our superior 8-Hydroxyadenosine Analysis Service. We utilize an advanced LC-MS/MS platform for the analysis of 8-Hydroxyadenosine. Our team of experts are capable of providing detailed insights into the levels of 8-Hydroxyadenosine in your samples, aiding you in your metabolic profiling studies.

       

      Analysis Workflow

       

      1833053598788472832-Workflowfor8-hydroxyadenosineAnalysisService.png

       

      Service Advantages

      • Continuously refined protocols and cutting-edge analytical tools  
      • Expert experimental planning  
      • Rapid processing times  
      • Exceptional precision, selectivity, and sensitivity

       

      Applications

      Our 8-Hydroxyadenosine Analysis Service can be applied in:

      • Biomarker discovery for oxidative stress-related diseases
      • Metabolic profiling studies
      • Drug metabolism studies

       

      Sample Submission Requirements

       

      1833051430727569408-SampleSubmissionRequirementsof8-hydroxyadenosineAnalysisService.png

       

      • Samples should be stored at -80℃ and shipped with dry ice.
      • We recommend providing at least 3 samples of similar conditions for each type of sample.
      • Please provide details on sample collection and handling.
      • Other sample types, please contact us for more details.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on 8-hydroxyadenosine

      4. Raw Data

      5. Custom Analysis Report

       

      Contact MtoZ Biolabs today to take advantage of our 8-Hydroxyadenosine Analysis Service. We look forward to assisting you in your research endeavors.

    Submit Inquiry
    Name *
    Email Address *
    Phone Number
    Inquiry Project
    Project Description *

     

    How to order?


    /assets/images/icon/icon-message.png

    Submit Inquiry

    /assets/images/icon/icon-return.png