Accurate Mass Determination Service

Accurate mass determination can be applied to all areas involved in chemistry and biochemistry. It is used to identify unknown compounds in complex mixtures, thereby simplifying the identification of all components. The accuracy of the determination refers to the degree of proximity between the measured value and its true value. In recent years, the mass determination of biological samples has received increasing attention, and at the same time, accurately determining the mass of these compounds has faced new challenges. Various instruments, especially advancements in MS, have made the application of accurate mass determination through MS more widespread.

 



Figure 1. Accurate Mass Determination

 

MtoZ Biolabs offers precise mass determination services for proteins, oligonucleotides, and oligosaccharides. MtoZ Biolabs mass spectrometry laboratory ensures more reliable and accurate determination results by regularly calibrating instruments, maintaining equipment, and establishing standard curves.

 

Sample Submission Requirements

We recommend using high quality solid samples or solutions. If you want to know the specific requirements for special samples, welcome to contact us.

 

MtoZ Biolabs uses the most advanced mass spectrometer-the Thermo Scientific Orbitrap Fusion Lumos-coupled with nanoLC-MS/MS nano-scale chromatography, to perform accurate mass determinations with high resolution and precision.

 

Servie at MtoZ Biolabs

1. Sample Processing Procedure
2. Experimental Methods and Steps
3. Raw Data
4. Data Analysis Report

• • Protein Complex Identification Service

  Mass spectrometry for identifying protein molecular weight requires minimal sample consumption and offers high sensitivity, resolution, and accuracy, facilitating the analysis of complex mixtures. Two primary types of mass spectrometry are widely used in protein identification:MALDI-TOF-MS: This technique directly measures molecular weight. ESI-MS: This high-resolution mass spectrometry technique analyzes the multiply charged signals produced by electrospray ionization.

• • Molecular Weight Determination Service

  Molecular weight is a basic physicochemical parameter of organic compounds, generally referring to the relative molecular mass, which is the sum of the relative atomic masses of each atom in the compound's chemical formula. The correctness of the molecular weight often represents whether the structure of the measured organic compound or biomacromolecule is accurate.

• • Protein Molecular Weight Determination Service

  Protein Mass Measurement can be applied to accurately analyze the molecular mass, subunits, and dimerization/polymerization of multiple biotechnological molecules.