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    Acenocoumarol Analysis Service

      Acenocoumarol is a synthetic anticoagulant that belongs to the coumarin class of drugs. It is used clinically to prevent and treat thromboembolic disorders, such as deep vein thrombosis and pulmonary embolism. Like other coumarin derivatives, acenocoumarol works by inhibiting the synthesis of vitamin K-dependent clotting factors (including prothrombin, Factor VII, IX, and X), thereby preventing blood coagulation. The chemical structure of acenocoumarol is 4-hydroxy-3-(1-(4-nitrophenyl)-3-oxobutyl)-2H-chromen-2-one, with a molecular formula of C19H15NO6. It features a coumarin ring system with a side chain containing a nitrophenyl group. Acenocoumarol is a white to pale yellow crystalline powder, slightly soluble in water but more soluble in organic solvents like alcohols and acetone. As a commonly used anticoagulant, acenocoumarol is valued for its ability to be precisely monitored and adjusted based on individual patient response, making it an important option in the management of clotting disorders. Despite the availability of newer anticoagulants, acenocoumarol remains a significant drug in clinical practice due to its well-established efficacy and safety profile.

       

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      Figure 1. The Structure of Acenocoumarol

       

      MtoZ Biolabs offers a cutting-edge Acenocoumarol Analysis Service, utilizing our advanced high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) platform and expert metabolomics team. Our service provides a comprehensive acenocoumarol analysis, ensuring high sensitivity and accuracy.

       

      Analysis Workflow

       

      1826150866039197696-WorkflowofAcenocoumarolAnalysisService.PNG

       

      Service Advantages

      1. Continuously Updated. At MtoZ Biolabs, we maintain a comprehensive laboratory network staffed with professional technicians, offering reliable plant-targeted metabolomics services and providing real-time updates on industry developments.

       

      2. One-Stop Service. Our laboratory is equipped to meet the needs of clients seeking third-party testing services or wishing to outsource their monitoring and analysis projects, delivering personalized one-on-one, one-stop service.

       

      3. Professional and Reliable. MtoZ Biolabs conducts warfarin analysis under strict quality, health, safety, and ethical control standards, and has earned multiple industry certifications, ensuring the highest level of professionalism and reliability.

       

      Applications

      • Qualitative analysis of the metabolites of acenocoumarol
      • Quantitative analysis of acenocoumarol content
      • Determination of acenocoumarol's pharmacological effects
      • Safety and quality assessment of acenocoumarol-containing products
      • Basis for improvement of acenocoumarol formulations

       

      Sample Submission Requirements

      1. Sample Types

      • Serum, plasma, urine, tissues, and other biological samples, pharmaceuticals.
      • It is necessary to select more than 3 samples with the same condition for each sample type.

       

      2. Sample Volume

      • At least 200 μL of liquid sample
      • At least 200 mg of animal tissues
      • At least 1 g of plant tissues

       

      3. Sample Preservation

      Store at -80°C to maintain stability.

       

      Note: Provide details on sample collection and handling.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on Acenocoumarol

      4. Raw Data

      5. Custom Analysis Report

       

      Through our acenocoumarol analysis service, we aim to facilitate your research and product development processes by providing accurate and reliable results.

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