Acetyl-CoA Analysis Service

Acetyl-CoA, an essential metabolite involved in various biochemical processes, plays pivotal roles in the Krebs cycle, fatty acid metabolism, and protein acetylation. Misregulation of acetyl-CoA metabolism has been linked to numerous diseases, including cancer and neurodegenerative diseases. Despite its importance, the quantification and characterization of acetyl-CoA presents significant challenges due to its high reactivity and instability.

 



 

Figure 1. The Structure of Acetyl-CoA

 

Services at MtoZ Biolabs

At MtoZ Biolabs, we utilize a robust and sensitive mass spectrometry-based method for acetyl-CoA analysis. Our approach includes advanced sample preparation protocols to stabilize acetyl-CoA and high-resolution mass spectrometry for accurate quantification and comprehensive metabolite profiling.

 



 

Applications

Our acetyl-CoA analysis service is applicable to a wide range of research areas, including but not limited to:

• Understanding acetyl-CoA metabolism in various biological processes.
• Identifying potential biomarkers related to acetyl-CoA metabolism.
• Investigating the role of acetyl-CoA in disease development and progression.
• Evaluating the effect of drugs on acetyl-CoA metabolism.

 

Sample Submission Requirements

• We accept various types of samples including plasma, cell lysates, tissue homogenates and urine.
• Please ensure your submitted sample surpasses 0.2 g or 0.2 mL.
• Samples should be stored in a -80℃ environment and transported on dry ice.

 

Deliverables

1. Experimental Procedures

2. Relevant Mass Spectrometry Parameters

3. Detailed Information on Acetyl-CoA Analysis

4. Mass Spectrometry Images

5. Raw Data

 

At MtoZ Biolabs, we are committed to providing you with quality acetyl-CoA analysis service to advance your research. Contact us today to discuss your project requirements.