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    Acetylcholine Analysis Service

      Acetylcholine (ACh) is a neurotransmitter found throughout the body, predominantly in the nervous system. It plays key roles in a plethora of physiological processes such as muscle contraction, heart rate, memory, and learning. ACh is synthesized from acetyl coenzyme A (acetyl-CoA) and choline, catalyzed by choline acetyltransferase in nerve terminals. An imbalance in ACh levels or the enzymatic systems related to its metabolism can lead to various disorders, including Alzheimer's, Parkinson's, and myasthenia gravis.

       

      Investigating the levels and metabolism of ACh can provide valuable insights into the physiological and pathological processes where it is implicated. ACh analysis is crucial for the diagnosis and monitoring of neurological disorders, the development of novel therapeutic strategies, and the advancement of neurobiological research.

       

      1831627824923529216-TheStructureofAcetylcholine.png

       

      Figure 1. The Structure of Acetylcholine

       

      At MtoZ Biolabs, we offer a comprehensive Acetylcholine Analysis Service using cutting-edge mass spectrometry technology. Our service can help you accurately quantify ACh levels in a variety of sample types, study its metabolic pathways, and investigate its role in various physiological and pathological states.

       

      Analysis Workflow

      1. Sample Preparation: Samples are carefully prepared to preserve the integrity of ACh.

      2. Metabolite Extraction: ACh is extracted using validated protocols to ensure maximum recovery.

      3. Mass Spectrometry Analysis: ACh levels are accurately quantified using mass spectrometry.

      4. Data Processing and Interpretation: The raw data are processed and interpreted with advanced bioinformatics tools.

      5. Report Generation: A detailed report including methodology, results, and interpretation is provided.

       

      1831626890990440448-WorkflowforAcetylcholineAnalysisService.png

       

      Service Advantages

      • State-of-the-art Mass Spectrometry Platforms: We utilize advanced mass spectrometry platforms, ensuring high sensitivity, accuracy, and reproducibility of ACh analysis.
      • Expert Team: Our team of experienced scientists and technicians are dedicated to providing the highest quality service and results.
      • Customizable Service: We can adapt our service to suit your specific research needs and objectives.
      • Comprehensive Report: We provide a comprehensive report detailing the analysis results, interpretations, and potential applications.

       

      Applications

      Our ACh Analysis Service can be applied in various research fields, including:

      • Neurobiology: Investigating the role of ACh in neurological disorders.
      • Drug Development: Development and evaluation of drugs targeting ACh system.
      • Clinical Research: Diagnosing and monitoring diseases related to ACh imbalance.

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues and other biological samples. For each sample, more than 3 materials of the same condition must be selected.

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

      Samples should be stored at -80°C to maintain stability.

       

      Note: Please provide details on sample collection and handling.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on Acetylcholine

      4. Raw Data

      5. Custom Analysis Report

       

      If you have any questions about our Acetylcholine Analysis Service or would like to discuss your research needs, please don't hesitate to contact us. We look forward to assisting you with your research.

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