Advanced 4D Proteomics Services at MtoZ Biolabs

At MtoZ Biolabs, we are proud to introduce our advanced 4D Proteomics services, designed to cater to the evolving needs of the scientific community. Our state-of-the-art technology leverages the timsTOF Pro system, integrating Trapped Ion Mobility Spectrometry (TIMS) and Parallel Accumulation Serial Fragmentation (PASEF) to deliver unmatched speed and sensitivity in protein analysis.

 



Figure1. Principle of 4D Proteomics Technology

 

Unraveling Proteomic Complexities with Precision

Our 4D Proteomics technology stands at the forefront of proteomic analysis by incorporating a 3D ion mobility spectrum that encompasses retention time and collision cross-section (CCS) measurements, alongside traditional mass spectrometry data. This fourth dimension of data acquisition allows for a more refined analysis, providing insights with greater accuracy and depth.

 

Comprehensive Proteomic Analysis Techniques

 

1. 4D-Label Free Proteomics

Utilizing a label-free approach, our services facilitate an extensive exploration of the proteome, enabling rapid data processing with minimal sample preparation. This technique supports high-throughput analysis, capable of handling up to 30 samples per day, which is ideal for large-scale studies.

 

2. 4D-DIA (Data Independent Acquisition)

Our DIA technique captures a vast range of m/z values, preserving all precursor ions. This method ensures exhaustive data collection across all samples, enabling deep proteome coverage and a throughput of up to 30 samples daily.

 

3. 4D Targeted Proteomics

For researchers focused on specific proteins, our targeted proteomics offers precise quantification and robust data analysis, supporting detailed studies on protein abundance and functionality.

 

4. 4D Ion Mobility Separation

Enhancing the resolution and peak capacity, our ion mobility separation tackles the complexity of sample matrices, facilitating improved peptide and protein separation and identification.

 

5. 4D-CCS Informed Proteomics

Incorporating CCS values aids in enhancing the certainty of peptide identifications. This additional layer of data enriches the quality and confidence of the analytical results, crucial for accurate biomarker discovery.

 

Tailored to Your Research Needs

MtoZ Biolabs’ 4D Proteomics services are ideally suited for a wide range of applications, from biomarker discovery and therapeutic target identification to in-depth systems biology research. Our technology is particularly beneficial for projects requiring high-throughput analysis with precise, reliable results.

 

Contact Us

Explore how MtoZ Biolabs' 4D Proteomics services can elevate your research by providing deeper insights and more reliable data. Contact us to learn more about how we can support your scientific endeavors with our cutting-edge technologies and expert analysis.