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    Alpha-Linolenic Acid Metabolism Service

      Alpha-linolenic acid (ALA) is an essential omega-3 fatty acid primarily derived from plant sources such as flaxseed, chia seeds, and walnuts. In living organisms, ALA plays a crucial role as a precursor in the biosynthesis of longer-chain omega-3 fatty acids, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). The metabolism of ALA involves a series of enzymatic reactions, including desaturation and elongation processes. Key enzymes, such as Δ⁶-desaturase and Δ⁵-desaturase, facilitate the conversion of ALA into EPA, which can further be elongated to DHA. These metabolites are integral to cellular membrane structure and function, anti-inflammatory processes, and neural development. Disruptions in ALA metabolism have been linked to various health issues, including cardiovascular diseases, inflammatory conditions, and cancer, underscoring the importance of comprehensive metabolic research in these areas. At MtoZ Biolabs, we offer top-notch Alpha-Linolenic Acid Metabolism Service to shed light on the metabolomic profile related to ALA metabolism.

       

      Services at MtoZ Biolabs

      MtoZ Biolabs is an industry-leading provider of mass spectrometry and metabolomics services. We are equipped with advanced analytical platforms, including LC-MS, GC-MS, and NMR, and boast an expert team passionate in metabolomics and lipidomics research. Our mission is to provide precise and reliable analytical services to accelerate scientific research and development.

       

      Our Alpha-Linolenic Acid Metabolism Service relies on liquid chromatography-mass spectrometry (LC-MS), a powerful tool for the detection and quantification of metabolites. LC-MS couples the separating power of liquid chromatography with the detection specificity of mass spectrometry, enabling the comprehensive analysis of metabolites involved in ALA metabolism.

       

      Analysis Workflow

      1. Sample Collection: Clients submit biological samples according to our sample submission guidelines.

      2. Sample Preparation: We perform sample extraction, purification, and derivatization to prepare samples for LC-MS analysis.

      3. LC-MS Analysis: We conduct LC-MS analysis to identify and quantify metabolites related to ALA metabolism.

      4. Data Processing and Analysis: We use powerful bioinformatics tools to process, normalize, and analyze the LC-MS data.

      5. Report Delivery: We provide a detailed report including methodology, results, and interpretation.

       

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      Service Advantages

      • Advanced LC-MS equipment with high sensitivity and accuracy
      • Comprehensive data analysis supported by a team of experienced analysts
      • Strict quality control to ensure reliable results
      • Personalized service to meet various research needs

       

      Applications

      Our Alpha-Linolenic Acid Metabolism Service is suitable for researchers in various fields including but not limited to:

      • Nutritional research: Understanding how diet influences ALA metabolism.
      • Pharmaceutical research: Evaluating the effect of drugs on ALA metabolism.
      • Clinical research: Identifying biomarkers related to diseases involving ALA metabolism.

       

      Sample Submission Requirements

      • Type of samples: Plasma, serum, cell, tissue, etc.
      • Quantity: At least 200 μl liquid, 1 x 10⁷ cells, or 200 mg tissue.
      • Storage and Shipping: Samples should be stored at -80℃ and shipped with dry ice.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Mass Spectrometry Parameters

      3. Detailed Information on Alpha-Linolenic Acid Metabolism Analysis

      4. Mass Spectrometry Images

      5. Raw Data

       

      At MtoZ Biolabs, we are committed to providing you with reliable and high-quality Alpha-Linolenic Acid Metabolism Service. Please feel free to contact us for more information.

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