Aniline Analysis Service
- Extensive expertise in handling various biological samples and extracting metabolites.
- State-of-the-art mass spectrometry platforms.
- Strict quality control to ensure reliable results.
- Comprehensive statistical and bioinformatics analysis.
- Personalized service to meet various research needs.
- Risk assessment of aniline exposure
- Evaluation of aniline-related health issues
- Detection of aniline in environmental samples
- Investigation of aniline metabolic pathways
- Development of aniline-based therapeutic agents
- Environmental samples ≥ 10 mL
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
Aniline is an aromatic amine with the molecular formula C₆H₇N. It consists of a benzene ring attached to an amino group (-NH₂), which contributes to its aromaticity and electron-rich nature. The lone pair of electrons on the nitrogen atom can participate in the π-electron cloud of the benzene ring, slightly decreasing the basicity of the amino group while making aniline more reactive toward electrophilic substitution reactions compared to benzene. Due to its aromatic structure and electron-donating properties, aniline is present in many industrial chemicals and pharmaceutical compounds. Its derivatives exhibit a wide range of biological activities, including analgesic, antipyretic, and anti-inflammatory effects. Aniline derivatives are found in various drug molecules, such as acetaminophen (paracetamol), sulfonamides, and certain dyes used in the textile and food industries.
Changes in the levels of aniline and its metabolites in the body may reflect specific exposure or health conditions. Because aniline is a precursor or structural unit in the synthesis of many important industrial and biological molecules, abnormal levels of its metabolites may be associated with various health issues, including hemolytic anemia, methemoglobinemia, and liver toxicity. Therefore, analyzing the levels of aniline and its metabolites can serve as potential biomarkers for exposure to toxic compounds or certain diseases, aiding in early diagnosis, monitoring of disease progression, and evaluating treatment efficacy. The metabolites of aniline can also reflect levels of oxidative stress in the body. The metabolism of aniline can produce various toxic intermediates, such as phenylhydroxylamine and nitrosobenzene, which can cause damage by reacting with cellular components. By monitoring the levels of aniline and its metabolites, it is possible to assess the degree of oxidative stress, thereby helping to develop targeted therapeutic and preventive measures.
Figure 1. The Structure of Aniline
MtoZ Biolabs is proud to introduce our top-tier Aniline Analysis Service, powered by our state-of-the-art liquid chromatography-mass spectrometry (LC-MS) platform and an expert team of metabolomics specialists. Our service guarantees comprehensive aniline analysis to meet researchers' needs.
Analysis Workflow
Service Advantages
Applications
Sample Submission Requirements
1. Sample Types
Environmental samples, serum, plasma, urine, tissues, and other biological samples. It is necessary to select more than 3 materials with the same condition for each sample.
2. Sample Volume
3. Sample Preservation
Store at -80°C to maintain stability.
Note: Provide details on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Aniline
4. Raw Data
5. Custom Analysis Report
Our Aniline Analysis Service is committed to supporting your research and product development by providing precise and reliable results. Trust MtoZ Biolabs for all your metabolomics analysis needs.
How to order?
