Arecoline Analysis Service
- High Sensitivity and Accuracy: LC-MS technology can precisely identify and quantify trace components in complex samples.
- Broad Applicability: Suitable for various biological samples, including plant tissues, blood, and urine.
- Rapid Analysis: The process from sample handling to report generation is efficient, shortening the analysis cycle.
- Customized Services: Personalized analysis solutions provided based on specific customer needs.
- Tissue Samples: > 200 mg
- Plasma Samples: > 200 μL
- Whole Blood Samples: > 500 μL
- Cell or Bacterial Samples: > 10^7 cells, > 2 mL supernatant
- Pharmaceutical Samples: > 0.2 g
Arecoline, a well-documented muscarinic acetylcholine receptor agonist, plays a significant role in both medical research and therapeutic applications, particularly in enhancing gastrointestinal motility and vascular integrity. However, its association with severe health risks, including submucous fibrosis and oral cancer, underscores the necessity for its meticulous analysis to ascertain both efficacy and safety.
Figure 1. Molecular Structure of Arecoline
MtoZ Biolabs utilizes liquid chromatography-mass spectrometry (LC-MS) for metabolomic analysis of arecoline. This technique combines the high separation efficiency of high-performance liquid chromatography (HPLC) with the high sensitivity of mass spectrometry (MS), allowing for the precise detection and quantification of trace components in complex samples. Our services extend beyond identification and quantification to include in-depth studies on the structure-activity relationships, metabolic pathways, and biological activity of alkaloids, providing comprehensive data support.
Analysis Workflow
Services at MtoZ Biolabs
Service Advantages
Sample Submission Requirements
To ensure robustness and reliability of the analysis, submission of at least six biological replicates is recommended, with all samples maintained under controlled conditions to minimize variability and enhance the precision of the results.
Applications
Gastrointestinal Research: Evaluating Arecoline’s efficacy in stimulating digestive processes.
Vascular Health: Exploring the protective role of Arecoline against endothelial damage and its efficacy in atherosclerosis prevention.
Oncological Studies: Assessing the link between Arecoline usage and oral cancer mechanisms, offering valuable insights for prevention and therapeutic strategies.
Pharmaceutical Development: Leveraging Arecoline's bioactive properties to innovate in the realms of antithrombotic and antimicrobial drug development.
At MtoZ Biolabs, we are dedicated to offering superior metabolomic analysis services for arecoline, aimed at enhancing your understanding of its biological functions and assisting in the development and regulatory compliance of associated products. We are eager to support your research endeavors as a trusted scientific partner.
How to order?
