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    Ascorbate and Aldarate Metabolism Service

      Ascorbate, commonly known as vitamin C, is a crucial antioxidant and cofactor in numerous enzymatic reactions across a variety of biological systems. It is essential for the synthesis of collagen, a structural protein vital for skin, cartilage, and bones, as well as for the maintenance of the immune system and the neutralization of free radicals. Ascorbate also plays a role in the regeneration of other antioxidants, contributing to cellular defense mechanisms. Aldarates, which are sugar acids derived from the oxidation of aldoses, are key intermediates in metabolic pathways such as the pentose phosphate pathway. This pathway is fundamental for the production of nucleotides and the maintenance of cellular redox balance, influencing DNA synthesis and repair, as well as lipid and neurotransmitter biosynthesis.

       

      In biological systems, the metabolism of ascorbate and aldarates is integral to maintaining cellular homeostasis and protecting against oxidative stress. Imbalances or deficiencies in these pathways can lead to a range of health issues, including scurvy, impaired wound healing, and increased susceptibility to infections. Additionally, research into these metabolic pathways can offer insights into aging processes, chronic diseases, and the development of targeted therapies or nutritional supplements.

       

      Services at MtoZ Biolabs

      MtoZ Biolabs has established a state-of-the-art platform for metabolomics analysis, equipped with LC-MS/MS, GC-MS/MS, HPLC, and UPLC system. Using our advanced technologies and professional expertise, we provide a comprehensive Ascorbate and Aldarate metabolism service. We employ LC-MS/MS and GC-MS/MS technologies for the identification and quantification of Ascorbate and Aldarate metabolites. These advanced technologies offer high-throughput detection, high resolution, and high sensitivity, thus providing accurate and reliable results.

       

      Analysis Workflow

      Our analysis workflow includes sample preparation, LC-MS/MS or GC-MS/MS analysis, data processing, and comprehensive statistical analysis. Our team of experts ensures that each step is meticulously performed to maintain the highest data quality.

       

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      Service Advantages

      • State-of-the-art mass spectrometry technology with high sensitivity and accuracy
      • Comprehensive data analysis supported by a team of experienced analysts
      • Strict quality control to ensure reliable results
      • Personalized service to meet various research needs

       

      Sample Submission Requirements

      To ensure high-quality results, please follow the sample submission guidelines:

      • For biofluids, please provide at least 200 µL of sample volume.
      • For tissue samples, please provide at least 200 mg of sample weight.
      • Samples should be stored in a -80℃ environment and transported on dry ice.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Mass Spectrometry Parameters

      3. Detailed Information on Ascorbate and Aldarate Metabolism Analysis

      4. Mass Spectrometry Images

      5. Raw Data

       

      For more information, please contact our customer service team. At MtoZ Biolabs, we are committed to providing high-quality, rigorous, and reliable results to help you advance in your research.

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