AUC Analysis of Antibody Drugs

Antibody drugs are a type of drugs that treat diseases through artificially synthesized antibodies, which bind specifically to target molecules for therapeutic purposes. Common types of antibody drugs include monoclonal antibodies, artificially synthesized antibody fragments, immunotoxins, and antibody-drug conjugates, etc. Antibody drugs have shown significant therapeutic effects in the treatment of various diseases such as cancer, autoimmune diseases, inflammatory diseases, immune regulation and ophthalmic diseases.

 

Analytical Ultracentrifugation (AUC) technology has a wide range of applications in the research and development of antibody drugs. AUC uses centrifugal force and centrifugation time to analyze the sedimentation behavior of molecules in the solution, which can provide important information about the structure, interactions, and purity of the drug. The specific applications of AUC in antibody drugs include:

 

1. Purity and aggregation analysis of antibody drugs.

2. Research on the interactions and complex formation of antibody drugs.

3. Evaluation of drug stability and aggregation kinetics.

4. Quality control in the development of antibody drugs.

 

This technology is widely used in the research and development process of antibody drugs and can provide important information about the structure, interactions, purity, stability, and aggregation kinetics of antibody drugs. This information is of great significance for the research and development, quality control, and efficacy evaluation of antibody drugs.