β-Muricholic Acid Analysis Service
- Evaluate the role of β-MCA in fat absorption and metabolism, supporting lipid metabolism studies.
- Analyze diseases related to bile acid metabolism, such as cholestasis, to help uncover their pathological mechanisms.
- Study the role of β-MCA in regulating gut microbiota, exploring its potential applications in metabolic diseases.
- Assess the impact of drugs on bile acid metabolism, supporting drug development and optimization of therapeutic strategies.
β-Muricholic acid (β-MCA) and α-muricholic acid (α-MCA) are two bile acids primarily found in the bile of rodents. They differ structurally in that β-MCA has a β-hydroxyl group at the 3-position on the A-ring, while α-MCA features an α-hydroxyl group at the same position. This structural distinction results in differences in their biological activities and metabolic pathways. β-MCA plays a unique role in regulating gut microbiota and lipid metabolism and is increasingly recognized for its potential in reducing lipid accumulation and improving metabolic health. In comparison, α-MCA also contributes to lipid metabolism, but its functions and metabolic characteristics are distinct from those of β-MCA.
Figure 1. Molecular Structure of β-Muricholic Acid
Given the significance of β-MCA in lipid metabolism research, bile acid metabolism disorders, and related diseases, accurate detection and analysis of β-MCA are essential. MtoZ Biolabs offers specialized β-Muricholic Acid Analysis Service, utilizing advanced high performance liquid chromatography (HPLC) and mass spectrometry (MS) technologies to provide clients with high-precision, high-sensitivity quantitative analysis, supporting scientific research and application development.
Analysis Workflow
Service Advantages
1. High Sensitivity and Specificity
Use high-resolution mass spectrometry instruments and optimized chromatographic conditions to ensure accurate identification and quantification of β-MCA.
2. Comprehensive Metabolite Coverage
Detect and analyze β-MCA and its related metabolites, providing a comprehensive metabolic profile.
3. Dynamic Change Analysis
Monitor dynamic changes in β-MCA levels under different conditions, revealing its role and regulatory mechanisms in metabolic pathways.
4. Efficient Data Analysis
Employ professional data analysis platforms to deliver detailed β-MCA information and interpret its biological significance.
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, feces, tissue extracts, and other biological samples.
2. Sample Volume
At least 200 μL of liquid sample or 200 mg of solid sample.
3. Sample Preservation
Store at -80°C to maintain stability.
Applications
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on β-Muricholic Acid
4. Raw Data
5. Custom Analysis Report
MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into β-MCA's extensive physiological roles through top-tier analytical techniques and expert services.
How to order?
