Carnitines

Carnitine is an amino acid-like compound crucial for fatty acid metabolism, especially in transporting and oxidizing long-chain fatty acids. It is predominantly found in muscles and the liver, aiding in the transport of fatty acids into mitochondria for β-oxidation and energy production. Additionally, carnitine is vital for cardiovascular health, athletic performance, and various disease states. Accurate analysis of carnitine and its metabolites is essential to understand their roles in health and disease.

 



Figure 1. General Chemical Structure of Carnitines

 

MtoZ Biolabs utilizes ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) for carnitine analysis. This advanced technology combines efficient UPLC separation with high-sensitivity MS/MS detection, ensuring accurate identification and quantification of various carnitine compounds and their metabolites in complex biological samples.

 

Analysis Workflow

 



 

Service Advantages

• High Sensitivity and Precision: UPLC-MS/MS provides highly sensitive and accurate measurements, capable of detecting low-abundance carnitine compounds.
• Rapid and Efficient: Optimized sample preparation and fast analysis ensure quick and efficient processing.
• Broad Applicability: Suitable for various biological samples, including blood, urine, and tissues.
• Accurate and Reliable Data: Ensures high reproducibility and low error rates, supporting both research and clinical applications, providing reliable and specific results.

 

Applications

Metabolic Research: Analyze the roles of carnitine in energy metabolism and metabolic disorders, studying its associations with obesity, diabetes, and other metabolic diseases.

 

Cardiovascular Health Research: Evaluate the role of carnitine in cardiovascular health, studying its effects on heart disease, atherosclerosis, and other conditions.

 

Sports Science: Monitor carnitine levels in athletes to optimize training and recovery strategies, enhancing athletic performance.

 

Disease Diagnosis and Treatment: Study changes in carnitine metabolism in various disease states, supporting clinical diagnosis and personalized treatment plans.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on Carnitines

4. Raw Data

5. Custom Analysis Report