Cholic Acid Analysis Service

    Cholic acid (CA) is a major primary bile acid widely found in the bile of humans and other mammals. It is synthesized from cholesterol in the liver and plays a crucial role in digestion, particularly in the absorption and metabolism of fats. As a primary bile acid, CA serves as a precursor to secondary bile acids, such as deoxycholic acid, within the intestine. Additionally, CA is essential for maintaining the dynamic balance of the bile acid pool, regulating cholesterol levels, and influencing gut microbiota metabolism.

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    Figure 1. Molecular Structure of Cholic Acid

     

    Abnormal CA metabolism is linked to various diseases, including cholestasis, cholesterol gallstones, and fatty liver disease. Therefore, accurate detection and analysis of CA are critical for understanding the mechanisms behind these diseases and for developing potential therapeutic strategies. MtoZ Biolabs offers specialized CA analysis services, utilizing advanced high performance liquid chromatography (HPLC) and mass spectrometry (MS) technologies to provide clients with high-sensitivity and high-specificity quantitative analysis, supporting scientific research and application development.

     

    Analysis Workflow

     

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    Service Advantages

    1. High Sensitivity and Precision

    HPLC-MS/MS provides highly sensitive and accurate measurements, suitable for detecting low concentrations of CA.

     

    2. Rapid and Efficient

    Optimized sample preparation and fast analysis ensure quick and efficient processing.

     

    3. Wide Applicability

    Suitable for various biological samples, including blood, urine, feces, and tissues.

     

    4. Accurate and Reliable Data

    Ensures high reproducibility and low error rates, supporting both research and clinical applications, providing reliable and specific results.

     

    Sample Submission Requirements

     

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    For detailed sample submission instructions, please consult our technical team.

     

    Applications

    • Analyze the role of CA in bile acid metabolism, supporting research into bile acid-related diseases.
    • Study the impact of CA on cholesterol level regulation, supporting cardiovascular disease research.
    • Evaluate the role of CA in regulating gut microbiota, exploring its potential applications in metabolic diseases.
    • Assess the impact of drugs on bile acid metabolism, supporting drug development and optimization of therapeutic strategies.

     

    Deliverables

    1. Experimental Procedures

    2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

    3. Detailed Information on Cholic Acid

    4. Raw Data

    5. Custom Analysis Report

     

    Our Cholic Acid Analysis Service provides high-quality data support, advancing your scientific research and applications. For any inquiries or requirements, please contact us.

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