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    Corticosterone Analysis Service

      Corticosterone, also known as 17-deoxycortisol and 11β,21-dihydroxyprogesterone, is a vital steroid hormone predominantly secreted by the adrenal cortex. As a major glucocorticoid, it is crucial for regulating stress responses, metabolic balance, immune functions, and fluid homeostasis. Maintaining normal corticosterone levels is essential for overall health, and deviations can lead to various health issues such as Cushing's syndrome, Addison's disease, metabolic syndrome, and immune disorders.

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      Figure 1. Molecular Structure of Corticosterone

       

      Corticosterone also significantly influences memory and cognitive functions. While appropriate levels of corticosterone aid in memory formation and consolidation, both excessively high and low levels can adversely affect cognitive processes. Elevated corticosterone over prolonged periods has been linked to cognitive decline and memory impairment, whereas insufficient levels can disrupt normal memory functions. Accurate measurement of corticosterone is crucial for understanding these effects, evaluating their impact on cognitive functions, and supporting the diagnosis and treatment of related conditions.

       

      MtoZ Biolabs offers Corticosterone Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in corticosterone detection.

       

      Analysis Workflow

       

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      Service Advantages

      • Rapid Analysis Cycle and Cost-Effectiveness
      • Stable, Reliable, and Highly Sensitive Results
      • Comprehensive One-Stop Service for Extensive Testing Needs
      • User-Friendly Operation with Wide Application Scope
      • Supported by Extensive Bioanalytical Resources and Advanced Platforms

       

      Sample Submission Requirements

      Make sure the sample volume is greater than 0.2 g or 0.2 mL. For detailed sample submission information, please contact our customer service.

       

      Applications

      1. Clinical Diagnosis: Assess and manage conditions associated with abnormal corticosterone levels, including Cushing's syndrome and Addison's disease.

       

      2. Stress Research: Study physiological responses to stress and variations in corticosterone levels.

       

      3. Memory and Cognitive Research: Investigate the role of corticosterone in memory and cognitive functions, and its implications in cognitive disorders.

       

      4. Disease Monitoring: Track changes in glucocorticoid levels to monitor disease progression and evaluate treatment efficacy.

       

      5. Health Management: Analyze corticosterone-related metabolic and immune issues to support health management decisions.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on Corticosterone

      4. Raw Data

      5. Custom Analysis Report

       

      Our Corticosterone Analysis Service provides high-quality data support, advancing your scientific research and applications. For any inquiries or requirements, please contact us.

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