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    dCMP Analysis Service

      Deoxycytidine monophosphate (dCMP) is a nucleotide that plays a fundamental role in DNA synthesis and repair. Structurally, dCMP consists of a cytosine base linked to a deoxyribose sugar and a single phosphate group. It is an essential building block of DNA, where it pairs with deoxyguanosine monophosphate (dGMP) to form the cytosine-guanine (C-G) base pairs that stabilize the DNA double helix. The availability and regulation of dCMP are critical for maintaining the fidelity of DNA replication and the integrity of genetic information during cell division.

       

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      Figure 1. The Structure of dCMP

       

      Research on dCMP and its metabolic pathways is pivotal in understanding various biological processes, including the cell cycle, DNA repair mechanisms, and the development of certain cancers. dCMP is synthesized from cytidine monophosphate (CMP) through the action of ribonucleotide reductase, a key enzyme in the conversion of ribonucleotides to deoxyribonucleotides. Disruptions in dCMP metabolism can lead to imbalances in nucleotide pools, contributing to genomic instability and the onset of diseases such as cancer. Moreover, the regulation of dCMP is of interest in the context of antiviral therapies, where analogs of dCMP are used to inhibit viral DNA synthesis.

       

      At MtoZ Biolabs, we provide comprehensive dCMP analysis service using high-resolution mass spectrometry, which can accurately quantify dCMP in your samples. Our team of experienced scientists and data analysts can help you interpret the results in a biological context, aiding in your research or clinical applications.

       

      Analysis Workflow

       

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      Service Advantages

      • Accuracy: Our high-resolution mass spectrometry equipment ensures accurate quantification of dCMP.
      • Experience: Our team of scientists and data analysts have extensive experience in dCMP analysis.
      • Comprehensive Report: We provide a comprehensive report detailing the analysis results and their biological significance.
      • Customizable Service: We offer customizable service packages to meet your specific needs.

       

      Applications

      Our dCMP analysis service can be used in a variety of applications, including:

      • Disease diagnosis and prognosis
      • Drug metabolism studies
      • Pharmacokinetic studies

       

      Sample Submission Requirements

       

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      • Samples should be stored at -80℃ and shipped on dry ice.
      • We recommend providing at least 3 samples of similar conditions for each type of sample.
      • Other sample types, please contact us for more details.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on dCMP

      4. Raw Data

      5. Custom Analysis Report

       

      At MtoZ Biolabs, we are committed to providing high-quality dCMP analysis service. Contact us today to learn more about our services.

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