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    Diosmin Analysis Service

      Diosmin is a naturally occurring flavonoid primarily found in citrus fruits. In plants, it is usually present in glycosidic form, combined with its aglycone counterpart. Diosmin is renowned for its excellent biological activities, particularly in vascular health. It can strengthen capillary resistance, reduce their fragility, and thus improve blood circulation. Diosmin also exhibits anti-inflammatory and antioxidant properties, capable of scavenging free radicals and reducing inflammation and oxidative stress damage to cells. Clinically, diosmin is commonly used in the treatment of varicose veins, hemorrhoids, and lymphedema. Additionally, diosmin possesses lipid-lowering and anticancer activities. Given its high safety profile and nontoxicity, diosmin has a wide range of applications in health care and drug development.

       

      1818826720129175552-TherapeuticActionofDiosmin.jpg

      Mustafa, S. et al. Curr Res Pharmacol Drug Discov. 2022.

      Figure 1. Therapeutic Action of Diosmin

       

      MtoZ Biolabs offers simple, fast, accurate, economical, and highly automated methods and equipment for analyzing diosmin. High-performance liquid chromatography-mass spectrometry (HPLC-MS) can effectively address challenges associated with diosmin analysis. Improved extraction and purification steps can enhance the sensitivity of the analysis, ensuring data accuracy and providing reliable reference points for researchers and clinicians.

       

      Analysis Workflow 

       

      1818550490934923264-WorkflowforDiosminbyHPLC-MSAnalysis.PNG

      Figure 2. Workflow for Diosmin by HPLC-MS Analysis

       

      Service Advantages

      • High Specificity and Resolution: Utilizing high-performance liquid chromatography combined with mass spectrometry detection, we ensure the specific identification and quantification of diosmin, avoiding confusion with other similar compounds.
      • Versatile Sample Analysis: Our services are suitable for a wide range of sample types, including plant extracts, food, beverages, and biological samples, meeting the needs of various research fields.
      • Rapid Turnaround and Flexible Service: We are committed to providing fast sample processing and data analysis services, supporting quick response for urgent projects, while also offering customized analytical solutions based on the specific needs of our clients.

       

      Applications

      • Drug Development: Diosmin is often used in the development of drugs for venous insufficiency and other vascular conditions. Accurate measurement of diosmin’s concentration and purity is vital for evaluating its therapeutic effects and formulating effective drugs.
      • Pharmacokinetics and Drug Interaction Studies: Evaluating diosmin’s absorption, distribution, metabolism, and excretion is crucial for understanding its behavior in the body and potential interactions with other drugs. MtoZ Biolabs supports these studies with precise analytical data.
      • Pharmaceutical Quality Control: Ensuring the quality and consistency of diosmin in pharmaceutical products. MtoZ Biolabs provides services to confirm that diosmin content meets required specifications, ensuring the effectiveness and safety of the final product.

       

      Sample Submission Requirements

      1. Fresh tissues of more than 1 g. If possible, samples should be frozen in liquid nitrogen immediately after collection and then transferred to -80°C for storage.

       

      2. Product samples.

      Please contact our customer service for detailed information on sample submission.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on Diosmin

      4. Raw Data

      5. Custom Analysis Report

       

      Our diosmin analysis service is designed to deliver accurate and reliable results, to streamline your research and product development processes.

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