Dynamic Light Scattering Particle Size Analysis

Dynamic Light Scattering (DLS) is a technique for assessing the dynamic behavior of particulate matter in solution. This technique is mainly aimed at particles on the nanometer to micron scale, and obtains particle size distribution by measuring the Brownian motion of particles in solution.

 

The basic principle of DLS is to scatter laser light onto the particle surface, and the particles move randomly and irregularly in Brownian motion, causing the intensity of scattered light to fluctuate over time. These light intensity fluctuations can be recorded by a photodetector and analyzed through a correlation function to obtain the dynamic properties of the particles.

 

Advantages

The main advantage of DLS is that it can analyze particle size distribution in real time, without any microscopic observation or operation of the sample. In addition, since DLS is a non-contact measurement technique, it can avoid any potential damage to the sample. Furthermore, DLS can also measure dynamic properties of particles, such as diffusion coefficients and viscosity, which are important for understanding and controlling particle behavior.

 

Applications

DLS has a wide range of applications in many fields, including pharmaceuticals, chemical engineering, materials science, etc. In the pharmaceutical field, DLS can be used to study drug nanoparticles, protein aggregation, etc. In the field of chemical engineering, DLS can be used to study the stability of emulsions, suspensions, etc. In the field of materials science, DLS can be used to study the behavior of nanomaterials, polymers, etc.

 

Dynamic Light Scattering Particle Size Analysis is a powerful particle analysis technique that can provide detailed information on particle size, shape, and dynamic behavior, which is of great significance for understanding and controlling particle behavior. In the future, with the development of nanotechnology and particle analysis technology, we have reason to believe that DLS will play its important role in more fields, bringing more surprises to our research and life.