Ethylmalonic Acid Analysis Service
- Rapid Analysis Cycle and Cost-Effectiveness
- Stable, Reliable, and Highly Sensitive Results
- Comprehensive One-Stop Service for Extensive Testing Needs
- User-Friendly Operation with Wide Application Scope
- Supported by Extensive Bioanalytical Resources and Advanced Platforms
- Monitor ethylmalonic acid levels to aid in diagnosing and managing metabolic diseases such as ethylmalonic aciduria.
- Investigate the role of ethylmalonic acid in inherited metabolic disorders, revealing gene mutations and pathological mechanisms.
- Assess the impact of drugs on ethylmalonic acid metabolism, supporting the development and evaluation of treatments for metabolic disorders.
- Analyze ethylmalonic acid content in food and supplements to optimize dietary strategies and health assessments.
Ethylmalonic acid is a significant organic acid with a critical role in human metabolism. It acts as a metabolic intermediate in energy metabolism and cellular regulation. Abnormal levels of ethylmalonic acid are linked to various metabolic disorders and genetic diseases, such as ethylmalonic aciduria (EMAc), a rare inherited metabolic condition causing the accumulation of ethylmalonic acid in the body. Accurate detection and quantification of ethylmalonic acid are essential for diagnosing, researching, and treating these conditions.
Figure 1. Molecular Structure of Ethylmalonic Acid
MtoZ Biolabs offers Ethylmalonic Acid Analysis Service using ultra-performance liquid chromatography-mass spectrometry (UPLC-MS). This advanced method combines the separation capabilities of UPLC with the detection power of MS, ensuring high sensitivity and specificity in ethylmalonic acid detection.
Analysis Workflow
Service Advantages
Sample Submission Requirements
1. Sample Types
Biological Fluids: Serum, plasma, urine, bile, bile acids
Animal Tissues: Cells, liver, brain, and other animal tissues, as well as feces
Other Samples: Plants, yeast, microorganisms
2. Sample Volume
At least 200 μL of liquid sample or 200 mg of solid sample.
3. Sample Transportation
For shipping, it is recommended to use an adequate amount of dry ice, considering that 3-4 kg of dry ice sublimates in one day. It is advisable to use larger blocks of dry ice as they sublimate more slowly. Ensure samples are sealed in a foam box and opt for the fastest possible shipping method to minimize sample degradation during transport.
Applications
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Ethylmalonic Acid
4. Raw Data
5. Custom Analysis Report
MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into ethylmalonic acid's extensive physiological roles through top-tier analytical techniques and expert services.
How to order?
