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    Fructose-6-phosphate Analysis Service

      Fructose-6-phosphate (F6P) serves as a crucial intermediary in both glycolysis and gluconeogenesis, processes central to the cellular metabolism of glucose. During glycolysis, under the enzyme phosphofructokinase-1 (PFK-1), F6P is transformed into fructose-1,6-bisphosphate (FBP), a reaction that contributes to a pathway culminating in the generation of ATP and pyruvate. In the pathway of gluconeogenesis, F6P plays a vital role in the synthesis of glucose-6-phosphate, which is critical for glucose production. Beyond these pathways, F6P acts as a precursor for synthesizing various essential biomolecules, including those involved in nucleotide and fatty acid synthesis, highlighting its versatility and pivotal function in cellular metabolism. This comprehensive role of F6P underscores its significance in bioenergetics and biosynthetic processes within the cell.

       

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      Figure 1. The Structure of Fructose-6-phosphate

       

      Services at MtoZ Biolabs

      Utilizing advanced liquid chromatography-mass spectrometry (LC-MS) techniques, MtoZ Biolabs can accurately separate and identify Fructose-6-phosphate, providing precise information on its molecular weight and structure. For quantitative analysis, we employ high-performance liquid chromatography (HPLC) with ultraviolet-visible (UV-Vis) detection to determine its content in various samples, helping to study its distribution and metabolism in different biological systems.

       

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      Service Advantages

      • High Sensitivity and Precision: Our advanced LC-MS technology ensures the high sensitivity and precision of F6P detection.
      • Professional Team: Our team of skilled technicians and scientists guarantees the accuracy and reproducibility of your results.
      • Comprehensive Solution: From sample submission to result delivery, we provide a comprehensive solution for your F6P analysis needs.

       

      Applications

      Our Fructose-6-phosphate Analysis Service can be applied in various research fields, including but not limited to:

      • Metabolic pathway research
      • Disease biomarker identification
      • Drug discovery and development

       

      Sample Submission Requirements

      • Sample amount: ≥200 mg of cell or tissue samples, or ≥200 µL of biofluid samples.
      • Storage condition: -80°C.
      • Shipping: Dry ice.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Mass Spectrometry Parameters

      3. Detailed Information on Fructose-6-phosphate Analysis

      4. Mass Spectrometry Images

      5. Raw Data

       

      At MtoZ Biolabs, we dedicate ourselves to providing the most reliable and precise Fructose-6-phosphate Analysis Service to meet your research needs. Contact us now to discuss your project with our experts.

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