Ganglio Series of Glycosphingolipid Analysis Service
- Precision: Our LC-MS/MS platform provides highly accurate and sensitive analysis.
- Comprehensive: We offer both qualitative and quantitative analysis of GSLs.
- Expertise: Our team is composed of professionals with deep knowledge in mass spectrometry and metabolomics.
- Timely: We ensure fast turnaround time without compromising on the quality.
- Investigation of the role of GSLs in diseases
- Understanding the biological function of GSLs
- Development of GSL-targeting therapeutics
- Validation of the efficacy of new drugs
- We accept various types of samples including plasma, serum, tissue, cells, and urine.
- Please ensure your submitted sample surpasses 0.5 g or 0.5 mL.
- Samples should be stored in a -80℃ environment and transported on dry ice.
Gangliosides are complex molecules consisting of glycosphingolipids, which include ceramide and oligosaccharides, attached to one or more sialic acids such as N-acetylneuraminic acid (NANA). These molecules are found in the plasma membrane, particularly concentrated in the nervous system, where they play crucial roles in modulating cell signal transduction. Recent studies have highlighted the significant immunological functions of gangliosides, suggesting that both natural and semi-synthetic gangliosides may serve as potential treatments for neurodegenerative diseases. On the cell surface, gangliosides contribute to cell recognition and communication, with their oligosaccharide moieties acting as specific markers that influence tissue growth and differentiation, as well as being implicated in cancer development. Additionally, gangliosides serve as receptors for certain hormones and bacterial toxins, such as cholera toxin, facilitating the recognition of extracellular molecules.
Services at MtoZ Biolabs
Our Ganglio Series of Glycosphingolipid Analysis Service utilizes a highly sensitive and precise mass spectrometry-based platform. In this process, the glycosphingolipids are first extracted from the samples. The extracted GSLs are then subject to liquid chromatography separation and further analyzed by tandem mass spectrometry (LC-MS/MS). The data obtained from the mass spectrometry is processed and analyzed to provide detailed information about the molecular structure and quantity of the GSLs in the samples.
Analysis Workflow
Service Advantages
Applications
Our service can be applied in various research areas such as:
Sample Submission Requirements
Deliverables
1. Experimental Procedures
2. Relevant Mass Spectrometry Parameters
3. Detailed Information on Ganglio Series of Glycosphingolipid Analysis
4. Mass Spectrometry Images
5. Raw Data
At MtoZ Biolabs, we are dedicated to providing excellent services to advance your research. We look forward to assisting you with your glycosphingolipid analysis needs.
How to order?
