Gastrointestinal Diseases Metabolomics Service

Gastrointestinal diseases, including inflammatory bowel disease, gastric ulcers, and irritable bowel syndrome, are common clinical conditions that significantly impact the quality of life for many individuals. These diseases are associated with changes in various metabolic pathways. Through metabolomics research, we can gain a deeper understanding of the mechanisms behind these diseases and explore new therapeutic targets.

 

Services at MtoZ Biolabs

MtoZ Biolabs offers comprehensive metabolomics services for gastrointestinal diseases, aiming to reveal the pathogenesis of these conditions, identify biomarkers, and provide guidance for drug development. Our services include:

 

1. Identification and verification of metabolic markers for gastrointestinal diseases

2. Metabolic pathway analysis of gastrointestinal diseases

3. Research on food-microbe-host interactions

4. Metabolic effect study of anti-gastrointestinal disease drugs

 



Kelly, P. E. et al. Metabolites. 2022.

Figure1. Gastrointestinal Diseases Metabolomics Analysis

 

Experimental Instruments

 

Our analysis platforms include GC-MS, LC-MS, and UPLC-MS, which can screen thousands of metabolites from a single biological sample, providing a comprehensive method for exploring disease mechanisms.

 

1. Chromatography

• GC (Q Exactive) (- MS mode)
• HPLC: HILIC (+/- MS mode)
• HPLC: RP C18 (+/- MS mode)
• IC (- MS mode)

 

2. Mass Spectrometry

• Q Exactive MS
• Orbitrap Tribrid Mass Spectrometer

 

Service Advantages

• Targeted Focus: Specializing in gastrointestinal diseases, optimizing analysis strategies based on disease characteristics.
• Extensive Metabolite Detection: Capable of detecting hundreds to thousands of metabolites, thoroughly covering key biological pathways.
• Rich Data Interpretation Experience: With years of experience in metabolomics research related to gastrointestinal diseases, we provide precise data interpretation and research recommendations.

 

Sample Submission Requirements

• Sample Types: We accept a variety of biological samples including blood, urine, feces, and tissue.
• Minimum Sample Volume: At least 500 μL of blood or an equivalent volume of other sample types is required.
• Preservation and Transportation: Samples should be stored at -80°C and transported under cold chain conditions.

 

As a mature partner in biopharmaceutical research, MtoZ Biolabs has extensive experience in metabolomics analysis. We provide solutions for gastrointestinal diseases with a focus on metabolomics analysis, accelerating the exploration of new scientific horizons. Please contact us for more information. Looking forward to working with you.