Genkwanin Analysis Service
- High-Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS) Technology: Ensures high sensitivity detection and quantification of genkwanin in complex matrices.
- Accurate Quantification: We offer precise quantitative analysis, suitable for detecting trace amounts to high concentrations, catering to various research needs.
- Data Integrity and Reliability: Our validated analytical methods ensure the accuracy and reproducibility of the data.
- Drug Development: Evaluating the antioxidant, anti-inflammatory, and other effects of genkwanin to identify potential drug candidates.
- Functional Foods: Assessing the contribution of genkwanin in functional foods, such as antioxidants and anti-inflammatory agents.
- Traditional Medicine Quality Control: Analyzing genkwanin in traditional Chinese medicine (TCM) to ensure the quality and efficacy of herbal products.
Genkwanin is a naturally occurring flavonoid found in plants such as Daphne genkwa Siebold & Zucc., which is known for its traditional medicinal uses. Genkwanin appears as a yellow crystalline substance, soluble in organic solvents such as pyridine, dimethyl sulfoxide, and alkaline solutions, slightly soluble in ethanol, acetone, and ethyl acetate, and nearly insoluble in chloroform, ether, benzene, carbon disulfide, and petroleum ether. The synthesis of genkwanin starts with phenylalanine. It involves the action of phenylalanine ammonia-lyase (PAL) and cinnamate-4-hydroxylase (C4H), among other enzymes, ultimately leading to the formation of genkwanin.
Genkwanin has been shown to possess anti-inflammatory and antioxidant properties, which can help in reducing inflammation and oxidative stress in the body. Clinically, genkwanin is being explored for its potential use in treating conditions such as arthritis, cardiovascular diseases, and cancer. Additionally, it is utilized in cosmetic formulations for its skin-soothing and anti-aging properties. Due to its diverse applications, developing analytical methods for detecting genkwanin in plant metabolites is crucial. MtoZ Biolabs offers simple, rapid, accurate, cost-effective, and highly automated analytical methods and equipment for analyzing genkwanin. High-performance liquid chromatography-mass spectrometry (HPLC-MS) is a valuable tool in addressing some challenges associated with genkwanin analysis. Improved extraction and purification steps can also enhance the sensitivity of the analytical methods.
El, Menyiy, N. et al. Biomed Pharmacother. 2023.
Figure 1. Schematic Representation of the Genkwanin Biosynthesis Pathway
Analysis Workflow
Figure 2. Workflow for Genkwanin by HPLC-MS Analysis
Service Advantages
Applications
Sample Submission Requirements
1. Fresh tissues >1 g. Immediately after collection, samples should, if feasible, be frozen in liquid nitrogen and stored at -80°C.
2. Product samples.
For more detailed information about how to submit your samples, please get in touch with our customer service team.
Deliverables
1. Experimental Procedures
2. Essential Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Genkwanin
4. Raw Data
5. Custom Analysis Report
With our Genkwanin Analysis Service, we aim to catalyze your research and product development by offering accurate and reliable results.
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