Glycochenodeoxycholic Acid 3 Sulfate Disodium Salt Analysis Service

Glycochenodeoxycholic acid 3-sulfate disodium salt (GCDCA-3S) is a sulfated derivative of chenodeoxycholic acid (CDCA), formed by the attachment of a sulfate group to the 3rd hydroxyl position of the glycine-conjugated CDCA molecule. This metabolite is crucial for understanding the dynamics of bile acid metabolism, liver function, and bile acid regulation. GCDCA-3S has been shown to play significant roles in liver health, bile acid metabolism, and lipid homeostasis. Precise quantification of GCDCA-3S is therefore critical for elucidating its role in both physiological and pathological contexts.

 

Figure 1. Molecular Structure of Glycochenodeoxycholic Acid 3 Sulfate Disodium Salt

 

MtoZ Biolabs offers Glycochenodeoxycholic Acid 3 Sulfate Disodium Salt Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in GCDCA-3S detection.

 

Analysis Workflow

 



 

Service Advantages

1. High Sensitivity

Detects very low concentrations of GCDCA-3S accurately.

 

2. High Specificity

Differentiates GCDCA-3S from other compounds using mass spectrometry.

 

3. Rapid Analysis

Efficient sample preparation and fast detection processes for high-throughput analysis.

 

4. High Accuracy

Strict quality control ensures accuracy and reproducibility.

 

5. Versatility

Capable of analyzing GCDCA-3S and its related metabolites.

 

Sample Submission Requirements

1. Sample Types

Serum, plasma, urine, feces, tissue extracts, and other biological samples.

 

2. Sample Volume

At least 200 μL of liquid sample or 200 mg of solid sample.

 

3. Sample Preservation

Store at -80°C to maintain stability.

 

Note: Provide details on sample collection and handling.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on Glycochenodeoxycholic Acid 3 Sulfate Disodium Salt

4. Raw Data

5. Custom Analysis Report