Glycochenodeoxycholic Acid Analysis Service
- Rapid Analysis Cycle and Cost-Effectiveness
- Stable, Reliable, and Highly Sensitive Results
- Comprehensive One-Stop Service for Extensive Testing Needs
- User-Friendly Operation with Wide Application Scope
- Supported by Extensive Bioanalytical Resources and Advanced Platforms
Glycochenodeoxycholic acid (GCDCA) is a conjugated bile acid formed from the conjugation of chenodeoxycholic acid (CDCA) with glycine. Synthesized in the liver and secreted into bile, GCDCA eventually reaches the intestines, where it plays a crucial role in fat digestion and absorption. GCDCA is a key component of the bile acid cycle and is involved in regulating cholesterol metabolism and maintaining lipid homeostasis. Abnormally elevated levels of GCDCA are associated with various hepatobiliary diseases, including cholestasis and gallstones. Therefore, precise analysis of GCDCA is critical for diagnosing and researching these conditions.
Figure 1. Molecular Structure of Glycochenodeoxycholic Acid
MtoZ Biolabs offers Glycochenodeoxycholic Acid Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in GCDCA detection.
Analysis Workflow
Service Advantages
Sample Submission Requirements
For detailed sample submission instructions, please consult our technical team.
Applications
1. Hepatobiliary Disease Research: Study GCDCA level changes to understand its role in conditions such as cholestasis and gallstones.
2. Cholesterol Metabolism Research: Investigate GCDCA's involvement in cholesterol metabolism, providing insights for managing hypercholesterolemia.
3. Lipid Metabolism Research: Examine GCDCA's function in lipid digestion and absorption to uncover its potential role in metabolic disorders.
4. Drug Development: Explore GCDCA's metabolic pathways to support the development of bile acid modulators and related therapies.
5. Toxicity Assessment: Assess the toxic effects of GCDCA accumulation, particularly in the context of abnormal bile acid metabolism.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Glycochenodeoxycholic Acid
4. Raw Data
5. Custom Analysis Report
MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into GCDCA's extensive physiological roles through top-tier analytical techniques and expert services.
How to order?
