Glycosylphosphatidylinositol Anchor Analysis Service
- We accept various types of samples including plasma, serum, tissue, cells, and urine.
- Please ensure your submitted sample surpasses 0.5 g or 0.5 mL.
- Samples should be stored in a -80℃ environment and transported on dry ice.
Glycosylphosphatidylinositol (GPI) anchors are glycolipids that attach to the C-terminus of proteins, serving to anchor these proteins to the cell membrane. They play a critical role in a wide range of biological processes including signal transduction, protein sorting, and host-pathogen interactions, among others. Mutations in the GPI anchor biosynthesis pathway can lead to a group of disorders known as GPI anchor deficiencies (GPIBDs), which have severe clinical implications. Understanding the intricacies of GPI anchors is thus key to developing therapeutic strategies for GPIBDs. At MtoZ Biolabs, we provide a comprehensive GPI Anchor Analysis Service to help researchers uncover the hidden potential in these intriguing biomolecules.
Services at MtoZ Biolabs
MtoZ Biolabs utilizes state-of-the-art LC-MS/MS technology for GPI Anchor Analysis. Our procedure involves the extraction of GPI-anchored proteins, enzymatic release of the GPI anchors, and subsequent purification. The purified GPI anchors are then analyzed using LC-MS/MS, and the resulting data is interpreted using advanced bioinformatics tools. This approach allows for the detailed characterization of GPI anchors, including the identification of their lipid and sugar components, and the determination of their exact molecular structure.
Analysis Workflow
Sample Submission Requirements
Deliverables
1. Experimental Procedures
2. Relevant Mass Spectrometry Parameters
3. Detailed Information on Glycosylphosphatidylinositol Anchor Analysis
4. Mass Spectrometry Images
5. Raw Data
Let MtoZ Biolabs be your trusted partner in your GPI anchor research. Contact us today to learn more about our GPI Anchor Analysis Service.
How to order?
