Guanidinoethyl Sulfonate Analysis Service

Guanidinoethyl sulfonate (GES) is an important organic compound derived from arginine and plays a key role in various biological processes. Arginine is converted into guanidinoacetic acid through a series of enzymatic reactions in the body, which is further transformed into GES. As a metabolite of amino acids, GES is involved in amino acid metabolism, neurotransmission, and cellular signaling. Due to its structure containing guanidine and sulfonic acid groups, GES has unique functions in many biological and chemical reactions.

 

Changes in GES levels are associated with various health conditions, such as neurodegenerative diseases, metabolic disorders, and renal dysfunction. Research indicates that GES plays complex and diverse roles in these diseases. Therefore, accurate measurement and monitoring of GES levels are crucial for disease research and diagnosis.

 



Figure 1. Molecular Structure of Guanidinoethyl Sulfonate

 

MtoZ Biolabs offers Guanidinoethyl Sulfonate Analysis Service using liquid chromatography-tandem mass spectrometry (LC-MS/MS). This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of GES in complex biological matrices.

 

Analysis Workflow

 



 

Service Advantages

1. High Sensitivity and Precision

HPLC-MS/MS provides highly sensitive and accurate measurements, suitable for detecting low concentrations of GES.

 

2. Rapid and Efficient

Optimized sample preparation and fast analysis ensure quick and efficient processing.

 

3. Wide Applicability

Suitable for various biological samples, including blood, urine, and tissues.

 

4. Accurate and Reliable Data

Ensures high reproducibility and low error rates, supporting both research and clinical applications, providing reliable and specific results.

 

Sample Submission Requirements

Please ensure that the sample volume is greater than 0.2 g or 0.2 mL.

 

Applications

Neurodegenerative disease research: Study the role of GES in neurodegenerative diseases such as Alzheimer's and Parkinson's.

 

Metabolic disorder research: Evaluate the relationship between GES and metabolic syndrome and diabetes.

 

Renal dysfunction research: Discover the role of GES in renal insufficiency and related diseases.

 

Biomedical research: Apply in various biomedical studies to explore its role in cellular signaling and amino acid metabolism.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on GES

4. Raw Data

5. Custom Analysis Report

 

MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into GES's extensive physiological roles through top-tier analytical techniques and expert services