H-Glu(Leu-OH)-OH Analysis Service
- Qualitative and quantitative analysis of H-Glu(Leu-OH)-OH metabolites
- Pharmacological studies of H-Glu(Leu-OH)-OH
- Establish a basis for drug development and academic research
- Animal tissue ≥ 50 mg
- Plant tissue ≥ 100 mg
- Serum/ Plasma ≥ 100 μL
- Urine ≥ 1 mL
H-Glu(Leu-OH)-OH is a dipeptide composed of glutamic acid (Glu) and leucine (Leu). Glutamic acid is an acidic amino acid with a side chain carboxyl group (-COOH), which imparts a negative charge at physiological pH, making it polar and hydrophilic. This side chain enables glutamic acid to play a significant role in protein folding and function, particularly in electrostatic interactions and in maintaining the protein's structural integrity. Leucine, on the other hand, is a branched-chain amino acid with a nonpolar, hydrophobic side chain. This makes leucine critical in the formation of hydrophobic cores within proteins, contributing to the stability of their three-dimensional structures.
The dipeptide H-Glu(Leu-OH)-OH can serve as a useful model compound in studies of peptide structure and function. Its unique combination of an acidic, polar amino acid (glutamic acid) and a hydrophobic amino acid (leucine) allows researchers to investigate the interplay between hydrophilic and hydrophobic interactions in peptide folding and stability. Additionally, H-Glu(Leu-OH)-OH may be used in studies of enzyme specificity, peptide synthesis, and degradation pathways. While the individual dipeptide may not exhibit substantial biological activity, research on such small peptides contributes to a deeper understanding of the behavior and interaction of larger, more complex proteins.
Figure 1. The Structure of H-Glu(Leu-OH)-OH
MtoZ Biolabs utilizes its cutting-edge liquid chromatography-mass spectrometry (LC-MS) platform and an expert team of metabolomics to offer a comprehensive H-Glu(Leu-OH)-OH analysis service. This service ensures high sensitivity and accuracy in the analysis of H-Glu(Leu-OH)-OH.
Analysis Workflow
Service Advantages
1. Continuously optimized experimental protocols and advanced instrument
2. Professional experimental design
3. Rapid turnaround time
4. High accuracy, specificity, and sensitivity
Applications
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues and other biological samples. More than 3 materials with the same condition should be selected for each sample.
2. Sample Volume
3. Sample Preservation
Samples should be stored at -80°C to maintain stability. Detailed instructions on sample collection and handling will be provided.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on H-Glu(Leu-OH)-OH
4. Raw Data
5. Custom Analysis Report
Our H-Glu(Leu-OH)-OH analysis service aims to support your research and product development with accurate and reliable data.
How to order?