Heparan Sulfate/Heparin Analysis Service
- Expertise: Our team has extensive experience in the analysis of complex bio-samples using mass spectrometry.
- Advanced Technology: We utilize state-of-the-art HPLC-MS/MS equipment to provide accurate and reliable results.
- Fast Turnaround: Our efficient workflow ensures timely delivery of results.
- Comprehensive Report: We provide detailed analysis reports, including in-depth interpretation and expert insights.
- Drug Development: Characterization and quantification of HS/heparin in drug formulations.
- Disease Research: Investigation of the role of HS/heparin in disease progression.
- Biomarker Discovery: Identification of HS/heparin biomarkers for disease diagnosis and prognosis.
- For serum/plasma samples: Please submit a minimum of 200 µL serum/plasma per analysis.
- For tissue samples: Please submit a minimum of 500 mg tissue per analysis.
- For cell samples: Please submit a minimum of 1 × 107 cells per analysis.
Heparan sulfate (HS) and heparin are complex polysaccharides, primarily function as anticoagulants, pivotal in the prevention and treatment of thrombotic disorders. Heparin acts by enhancing the activity of antithrombin III, thereby inhibiting thrombin and factor Xa, crucial enzymes in the blood coagulation cascade. This inhibition is vital for preventing the formation of clots in blood vessels, which can lead to conditions such as deep vein thrombosis and pulmonary embolism. Heparin, due to its smaller size, has a more predictable pharmacokinetic profile than standard heparin, leading to its widespread use in clinical settings. However, due to their structural complexity and high negative charge, their analysis poses significant analytical challenges.
Services at MtoZ Biolabs
At MtoZ Biolabs, we understand the importance of accurate and reliable Heparan Sulfate/Heparin quantification. Our Heparan Sulfate/Heparin Analysis Service leverages advanced mass spectrometry technology and a team of experienced scientists to provide comprehensive characterization and quantification of these critical biomolecules. Our Heparan Sulfate/Heparin Analysis Service employs high performance liquid chromatography coupled with tandem mass spectrometry (HPLC-MS/MS). This technique allows for the efficient separation and identification of HS and heparin, even in complex biological samples. Additionally, our proprietary sample preparation protocol ensures optimal recovery and minimal sample loss.
Analysis Workflow
Service Advantages
Applications
Our Heparan Sulfate/Heparin Analysis Service is applicable in various research areas including but not limited to:
Sample Submission Requirements
Deliverables
1. Experimental Procedures
2. Relevant Mass Spectrometry Parameters
3. Detailed Information on Heparan Sulfate/Heparin Analysis
4. Mass Spectrometry Images
5. Raw Data
For more information, please contact MtoZ Biolabs. Our dedicated customer service team is ready to assist you in achieving your research goals.
How to order?
