Hexanoyl Glycine Analysis Service
- Qualitative analysis of the metabolites of hexanoyl glycine
- Quantitative analysis of hexanoyl glycine content
- Provide basis for pharmacological research
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
Hexanoyl glycine is a conjugate of hexanoic acid and glycine, and serves as a minor metabolite in fatty acid metabolism. It is particularly involved in the catabolism of medium-chain fatty acids, playing a crucial role in the body's energy production processes. In living organisms, hexanoyl glycine is formed through the glycine conjugation pathway, where hexanoic acid is activated and conjugated to glycine by the enzyme glycine-N-acyltransferase. This process facilitates the excretion of hexanoic acid, a medium-chain fatty acid, which can be toxic in elevated concentrations, thus helping to maintain metabolic homeostasis. Hexanoyl glycine can serve as a biomarker for various metabolic conditions, particularly those related to fatty acid oxidation disorders. Elevated levels of hexanoyl glycine in biological samples such as urine may indicate an underlying issue with fatty acid metabolism, such as medium-chain Acyl-CoA dehydrogenase deficiency (MCADD), a genetic disorder affecting the breakdown of medium-chain fatty acids. Monitoring hexanoyl glycine levels is thus important in diagnosing and managing metabolic disorders, as well as in assessing the impact of therapeutic interventions that target fatty acid metabolism.
Figure 1. The Structure of Hexanoyl Glycine
MtoZ Biolabs offers specialized hexanoyl glycine analysis service, leveraging an advanced technology platform and a skilled metabolomics research team. We provide accurate and reliable data to support your research in metabolic disorders, drug development, and clinical studies, ensuring the success of your projects through high-quality analytical services.
Analysis Workflow
Service Advantages
1. High quality data: We deliver reliable and reproducible results with our advanced LC-MS system.
2. Expertise: Our experienced team of scientists ensures the quality and accuracy of our analysis.
3. Comprehensive report: We provide a detailed report including the experimental procedure, instrument parameters, and results interpretation.
4. Fast turnaround: The process from sample handling to report generation is efficient, shortening the analysis cycle.
Applications
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues and other biological samples. A minimum of 3 samples with the same condition is required for each analysis.
2. Sample Volume
3. Sample Preservation
Store at -80°C to maintain stability.
Note: Provide details on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Hexanoyl Glycine
4. Raw Data
5. Custom Analysis Report
With our hexanoyl glycine analysis service, we aim to support your research and product development efforts by providing accurate and reliable results. Trust MtoZ Biolabs for your comprehensive hexanoyl glycine analysis needs.
How to order?
